{"paper":{"title":"Human Spermbots for Cancer-Relevant Drug Delivery","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.CB","authors_text":"Carla Ribeiro, Christine K. Schmidt, Daniel R. Brison, Elkin Lucena, Haifeng Xu, Kang Zeng, Lina P. Restrepo, Louisa Nelson, Mariana Medina-Sanchez, Oliver G. Schmidt, Richard J. Edmondson, Stephen S. Taylor, Steven Bagley","submitted_at":"2019-04-29T13:09:15Z","abstract_excerpt":"Cellular micromotors are attractive for locally delivering high concentrations of drug and targeting hard-to-reach disease sites such as cervical cancer and early ovarian cancer lesions by non-invasive means. Spermatozoa are highly efficient micromotors perfectly adapted to traveling up the female reproductive system. Indeed, bovine sperm-based micromotors have recently been reported as a potential candidate for the drug delivery toward gynecological cancers of clinical unmet need. However, due to major differences in the molecular make-up of bovine and human sperm, a key translational bottlen"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1904.12684","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}