{"paper":{"title":"Thermodynamic constraints on the citric acid cycle and related reactions in ocean world interiors","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":[],"primary_cat":"astro-ph.EP","authors_text":"Emre I\\c{s}{\\i}k, Jessica Weber, Mohit Melwani Daswani, Nazl{\\i} Olgun K{\\i}yak, Seda I\\c{s}{\\i}k","submitted_at":"2025-04-27T22:17:11Z","abstract_excerpt":"Icy ocean worlds attract significant interest for their astrobiological potential due to subsurface oceans, organics, and chemical energy sources. We quantify thermodynamic viability of metabolism-relevant reactions at pressure-temperature conditions of Enceladus, Europa, Titan, Ganymede, and the Lost City Hydrothermal Field for comparison. We examine the tricarboxylic acid (TCA) cycle and a plausible prebiotic reaction network leading to it, using DEWPython (based on the Deep Earth Water model) and SUPCRT to compute equilibrium constants and Gibbs free energy changes across temperatures from "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2504.19369","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2504.19369/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}