{"paper":{"title":"Quantifying Circadian Desynchrony in ICU Patients and Its Association with Delirium","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":["cs.AI"],"primary_cat":"q-bio.QM","authors_text":"Andrea E. Davidson, Ayush K. Patel, Azra Bihorac, Jiaqing Zhang, Michelle Gumz, Miguel Contreras, Parisa Rashidi, Tezcan Ozrazgat-Baslanti, Yuanfang Ren","submitted_at":"2025-03-11T03:56:10Z","abstract_excerpt":"Background: Circadian desynchrony characterized by the misalignment between an individual's internal biological rhythms and external environmental cues, significantly affects various physiological processes and health outcomes. Quantifying circadian desynchrony often requires prolonged and frequent monitoring, and currently, an easy tool for this purpose is missing. Additionally, its association with the incidence of delirium has not been clearly explored. Methods: A prospective observational study was carried out in intensive care units (ICU) of a tertiary hospital. Circadian transcriptomics "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2503.08732","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2503.08732/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}