{"paper":{"title":"Conformal inference for cell type annotation with graph-structured constraints","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["stat.AP"],"primary_cat":"stat.ME","authors_text":"Daniela Corbetta, Davide Risso, Livio Finos, Ludwig Geistlinger","submitted_at":"2024-10-31T10:00:40Z","abstract_excerpt":"Conformal prediction is a framework for constructing prediction sets for machine learning models, relying solely on the exchangeability of training and test data and without requiring to specify a parametric distribution. Despite its wide applicability and popularity, its application in single-cell transcriptomics remains underexplored. This paper addresses this gap by developing an approach that leverages the rich information about cell-type relations, encoded in the graph structure of cell ontologies, to enhance the interpretability of reference-based cell-type annotation. Leveraging conform"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2410.23786","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2410.23786/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}