{"paper":{"title":"Multi-species breath biomarker profiling with an ultra-broadband (2.9-11.5 {\\mu}m) spectroscopic platform","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"physics.optics","authors_text":"Amir Khodabakhsh, Joris Meurs, Kees van Kempen, Marleen Huisman, Roderik Krebbers, Simona M. Cristescu","submitted_at":"2026-05-19T17:23:03Z","abstract_excerpt":"Online, comprehensive molecular profiling of exhaled breath provides a non-invasive window into human metabolism, yet current optical platforms are restricted by narrow instantaneous spectral coverage. Here, we present a novel ultra-broadband mid-infrared spectroscopic platform that enables simultaneous, high-sensitivity detection of a comprehensive profile of breath biomarkers. By integrating an intrapulse difference-frequency generation (IDFG) supercontinuum source spanning 2.9-11.5 $\\mu$m (2580 cm$^{-1}$) with a custom-built Fourier transform spectrometer, we achieve a spectral resolution o"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2605.20139","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2605.20139/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}