{"paper":{"title":"Accelerating De Novo Genome Assembly via Quantum-Assisted Graph Optimization with Bitstring Recovery","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["q-bio.GN"],"primary_cat":"quant-ph","authors_text":"Ashwini Kannan, Himanshu Sahu, Janani Ananthanarayanan, Jaya Vasavi Pamidimukkala, Kalyan Dasgupta, Sanjib Senapati","submitted_at":"2026-01-29T19:03:55Z","abstract_excerpt":"Genome sequencing is essential to decode genetic information, identify organisms, understand diseases and advance personalized medicine. A critical step in any genome sequencing technique is genome assembly. However, de novo genome assembly, which involves constructing an entire genome sequence from scratch without a reference genome, presents significant challenges due to its high computational complexity, affecting both time and accuracy. In this study, we propose a hybrid approach utilizing a quantum computing-based optimization algorithm integrated with classical pre-processing to expedite"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2602.00156","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2602.00156/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}