{"paper":{"title":"Doxorubicin Loaded Magnetic Polymersomes: Theranostic Nanocarriers for MR Imaging and Magneto-Chemotherapy","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.mtrl-sci"],"primary_cat":"cond-mat.soft","authors_text":"Alain Brisson (CBMN), Alain Soum (LCPO), Annie Br\\^ulet (LLB), Charles Sanson (LCPO, Emmanuel Ibarboure (LCPO), Eric Thiaudi\\`ere (RMSB), Julie Thevenot (LCPO), LCPO, LCPO), Odile Diou (LCPO), Olivier Sandre (CNRS, S\\'ebastien Lecommandoux (LCPO), Sisareuth Tan (CBMN), Sylvain Miraux (RMSB), Univ . Bordeaux, Vincent Dupuis (PECSA)","submitted_at":"2012-09-23T19:03:34Z","abstract_excerpt":"Hydrophobically modified magnetic nanoparticles (MNPs) were encapsulated within the membrane of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA) block copolymer vesicles using a nanoprecipitation process. This formulation method provides a high loading of MNPs (up to 70 wt %) together with a good control over the sizes of the vesicles (100 - 400 nm). The deformation of the vesicle membrane under an applied magnetic field was evidenced by anisotropic SANS. These hybrid objects display contrast enhancement properties in Magnetic Resonance Imaging, a diagnostic method routinely u"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1209.5098","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}