{"paper":{"title":"DiSTILL: A Hybrid Cloud-HPC Workflow System for Reproducible Spatial Transcriptomics Analysis","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.GN","authors_text":"Kejun Huang, Maria Kapetanaki, Myles Joshua Toledo Tan, Nikhil Yerra, Panayiotis V. Benos, Parisa Rashidi, Vasco Gerardo Hinostroza Fuentes","submitted_at":"2026-06-28T23:00:28Z","abstract_excerpt":"Spatial transcriptomics workflows increasingly combine large annotated data objects, notebook-based analyses, and resource-intensive statistical models that must be executed on high-performance computing (HPC) systems. In practice, these workflows are often difficult to reproduce because configuration, validation, stage execution, and artifact handling are fragmented across $\\textit{ad hoc}$ scripts and manually edited notebooks. We present $\\textit{DiSTILL}$ (Disease Diagnosis from Spatial Transcriptomics via Interpretable Latent Learning), a hybrid cloud$-$HPC workflow system for reproducibl"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2606.30693","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2606.30693/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}