{"paper":{"title":"Probing the network structure of health deficits in human aging","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.soc-ph"],"primary_cat":"q-bio.PE","authors_text":"Andrew D. Rutenberg, Arnold B. Mitnitski, Kenneth Rockwood, Olga Theou, Spencer G. Farrell","submitted_at":"2018-02-23T19:30:16Z","abstract_excerpt":"We confront a network model of human aging and mortality in which nodes represent health attributes that interact within a scale-free network topology, with observational data that uses both clinical and laboratory (pre-clinical) health deficits as network nodes. We find that individual health attributes exhibit a wide range of mutual information with mortality and that, with a re- construction of their relative connectivity, higher-ranked nodes are more informative. Surprisingly, we find a broad and overlapping range of mutual information of laboratory measures as compared with clinical measu"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1802.08708","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}