{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2023:2J6GAHIFGLXF3O5VSNLMTR5KMM","short_pith_number":"pith:2J6GAHIF","canonical_record":{"source":{"id":"2310.01409","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2023-10-02T17:59:35Z","cross_cats_sorted":["physics.class-ph"],"title_canon_sha256":"5844849e3e0d642112b9a34075e153e3ab99bf8e57f4c954be18db0bb310e940","abstract_canon_sha256":"5a957e4b962daab6e0bc803ca85ca88a7b1674c893ee66a65d4d9ec552c37a72"},"schema_version":"1.0"},"canonical_sha256":"d27c601d0532ee5dbbb59356c9c7aa6334e89cf9e3d373b3df8c64fad21db279","source":{"kind":"arxiv","id":"2310.01409","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2310.01409","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"arxiv_version","alias_value":"2310.01409v1","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2310.01409","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"pith_short_12","alias_value":"2J6GAHIFGLXF","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"pith_short_16","alias_value":"2J6GAHIFGLXF3O5V","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"pith_short_8","alias_value":"2J6GAHIF","created_at":"2026-07-05T06:56:26Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2023:2J6GAHIFGLXF3O5VSNLMTR5KMM","target":"record","payload":{"canonical_record":{"source":{"id":"2310.01409","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2023-10-02T17:59:35Z","cross_cats_sorted":["physics.class-ph"],"title_canon_sha256":"5844849e3e0d642112b9a34075e153e3ab99bf8e57f4c954be18db0bb310e940","abstract_canon_sha256":"5a957e4b962daab6e0bc803ca85ca88a7b1674c893ee66a65d4d9ec552c37a72"},"schema_version":"1.0"},"canonical_sha256":"d27c601d0532ee5dbbb59356c9c7aa6334e89cf9e3d373b3df8c64fad21db279","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T06:56:26.293572Z","signature_b64":"3Dtbwh7iEoalULyQcdfNJZVs2mu3XO4F/TR8Y/k6f0Zk3a+3EqtEMhkR9nktJ1GrQYWK5L9JkyXlA/jamGrWCw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"d27c601d0532ee5dbbb59356c9c7aa6334e89cf9e3d373b3df8c64fad21db279","last_reissued_at":"2026-07-05T06:56:26.293035Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T06:56:26.293035Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2310.01409","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T06:56:26Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"prGueUVk2rid47nfeZxDcDW+2Lnsrbe21qxUkw86A3B80kiaxuvvqQsMcJxrEM5CoAaSF1yiPK5wts3+sHDSBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-16T05:21:53.542136Z"},"content_sha256":"f0a1cf32e6b5c4932b7309939b289e72ee42644745400618e6eea5035d7020dd","schema_version":"1.0","event_id":"sha256:f0a1cf32e6b5c4932b7309939b289e72ee42644745400618e6eea5035d7020dd"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2023:2J6GAHIFGLXF3O5VSNLMTR5KMM","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Direct Comparison of Isobaric and Isochoric Vitrification of Two Aqueous Solutions with Photon Counting X-Ray Computed Tomography","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["physics.class-ph"],"primary_cat":"physics.med-ph","authors_text":"Anthony N. Consiglio, Boris Rubinsky, Jason T. Parker, Simo A. M\\\"akiharju","submitted_at":"2023-10-02T17:59:35Z","abstract_excerpt":"Vitrification is a promising approach for ice-free cryopreservation of biological material, but progress is hindered by the limited set of experimental tools for studying processes in the interior of the vitrified matter. Isochoric cryopreservation chambers are often metallic, and their opacity prevents direct visual observation. In this study, we introduce photon counting X-ray computed tomography (CT) to compare the effects of rigid isochoric and unconfined isobaric conditions on vitrification and ice formation during cooling of two aqueous solutions: 50 wt% DMSO and a coral vitrification so"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2310.01409","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2310.01409/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T06:56:26Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"GYhLLfO6zi60IP4ZF6LHWyKVAIDxQFkOQffCV+nIPNQfoci0uJObj2l8790n1G3YJRfjdc78jJdrDEFBjcHCBw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-16T05:21:53.542642Z"},"content_sha256":"083c7819ec9744c19a4e907e9901fc0c208f85bfb76a3465f6218cf2aa13c1c0","schema_version":"1.0","event_id":"sha256:083c7819ec9744c19a4e907e9901fc0c208f85bfb76a3465f6218cf2aa13c1c0"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/2J6GAHIFGLXF3O5VSNLMTR5KMM/bundle.json","state_url":"https://pith.science/pith/2J6GAHIFGLXF3O5VSNLMTR5KMM/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/2J6GAHIFGLXF3O5VSNLMTR5KMM/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-16T05:21:53Z","links":{"resolver":"https://pith.science/pith/2J6GAHIFGLXF3O5VSNLMTR5KMM","bundle":"https://pith.science/pith/2J6GAHIFGLXF3O5VSNLMTR5KMM/bundle.json","state":"https://pith.science/pith/2J6GAHIFGLXF3O5VSNLMTR5KMM/state.json","well_known_bundle":"https://pith.science/.well-known/pith/2J6GAHIFGLXF3O5VSNLMTR5KMM/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2023:2J6GAHIFGLXF3O5VSNLMTR5KMM","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"5a957e4b962daab6e0bc803ca85ca88a7b1674c893ee66a65d4d9ec552c37a72","cross_cats_sorted":["physics.class-ph"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2023-10-02T17:59:35Z","title_canon_sha256":"5844849e3e0d642112b9a34075e153e3ab99bf8e57f4c954be18db0bb310e940"},"schema_version":"1.0","source":{"id":"2310.01409","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2310.01409","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"arxiv_version","alias_value":"2310.01409v1","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2310.01409","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"pith_short_12","alias_value":"2J6GAHIFGLXF","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"pith_short_16","alias_value":"2J6GAHIFGLXF3O5V","created_at":"2026-07-05T06:56:26Z"},{"alias_kind":"pith_short_8","alias_value":"2J6GAHIF","created_at":"2026-07-05T06:56:26Z"}],"graph_snapshots":[{"event_id":"sha256:083c7819ec9744c19a4e907e9901fc0c208f85bfb76a3465f6218cf2aa13c1c0","target":"graph","created_at":"2026-07-05T06:56:26Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2310.01409/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Vitrification is a promising approach for ice-free cryopreservation of biological material, but progress is hindered by the limited set of experimental tools for studying processes in the interior of the vitrified matter. Isochoric cryopreservation chambers are often metallic, and their opacity prevents direct visual observation. In this study, we introduce photon counting X-ray computed tomography (CT) to compare the effects of rigid isochoric and unconfined isobaric conditions on vitrification and ice formation during cooling of two aqueous solutions: 50 wt% DMSO and a coral vitrification so","authors_text":"Anthony N. Consiglio, Boris Rubinsky, Jason T. Parker, Simo A. M\\\"akiharju","cross_cats":["physics.class-ph"],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2023-10-02T17:59:35Z","title":"Direct Comparison of Isobaric and Isochoric Vitrification of Two Aqueous Solutions with Photon Counting X-Ray Computed Tomography"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2310.01409","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:f0a1cf32e6b5c4932b7309939b289e72ee42644745400618e6eea5035d7020dd","target":"record","created_at":"2026-07-05T06:56:26Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"5a957e4b962daab6e0bc803ca85ca88a7b1674c893ee66a65d4d9ec552c37a72","cross_cats_sorted":["physics.class-ph"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2023-10-02T17:59:35Z","title_canon_sha256":"5844849e3e0d642112b9a34075e153e3ab99bf8e57f4c954be18db0bb310e940"},"schema_version":"1.0","source":{"id":"2310.01409","kind":"arxiv","version":1}},"canonical_sha256":"d27c601d0532ee5dbbb59356c9c7aa6334e89cf9e3d373b3df8c64fad21db279","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"d27c601d0532ee5dbbb59356c9c7aa6334e89cf9e3d373b3df8c64fad21db279","first_computed_at":"2026-07-05T06:56:26.293035Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T06:56:26.293035Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"3Dtbwh7iEoalULyQcdfNJZVs2mu3XO4F/TR8Y/k6f0Zk3a+3EqtEMhkR9nktJ1GrQYWK5L9JkyXlA/jamGrWCw==","signature_status":"signed_v1","signed_at":"2026-07-05T06:56:26.293572Z","signed_message":"canonical_sha256_bytes"},"source_id":"2310.01409","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:f0a1cf32e6b5c4932b7309939b289e72ee42644745400618e6eea5035d7020dd","sha256:083c7819ec9744c19a4e907e9901fc0c208f85bfb76a3465f6218cf2aa13c1c0"],"state_sha256":"621359761430573b0214552303504f90db5a1a3e27b851c32c2616fead0020aa"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"BKcPP8gTMwWfcml7+Ov2TfXnFLs1R/v9PHvHhfnMvb8eycQ5dWTDx53FX51EQYDZ0OVaCV9VKQa7okqnyxphAA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-16T05:21:53.546638Z","bundle_sha256":"84e422d09f379a875b3ed17e30355e98f9fb988cafc393e8e023c70c57b9c60b"}}