{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2018:4MKOKAXA7XICQNTBMJAD2ZKQSQ","short_pith_number":"pith:4MKOKAXA","schema_version":"1.0","canonical_sha256":"e314e502e0fdd028366162403d65509437415f9b7a0f51d30e35430a680ab600","source":{"kind":"arxiv","id":"1805.12077","version":2},"attestation_state":"computed","paper":{"title":"Conservation Laws and Work Fluctuation Relations in Chemical Reaction Networks","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.MN"],"primary_cat":"cond-mat.stat-mech","authors_text":"Massimiliano Esposito, Riccardo Rao","submitted_at":"2018-05-30T16:50:34Z","abstract_excerpt":"We formulate a nonequilibrium thermodynamic description for open chemical reaction networks (CRN) described by a chemical master equation. The topological properties of the CRN and its conservation laws are shown to play a crucial role. They are used to decompose the entropy production into a potential change and two work contributions, the first due to time dependent changes in the externally controlled chemostats concentrations and the second due to flows maintained across the system by nonconservative forces. These two works jointly satisfy a Jarzynski and Crooks fluctuation theorem. In abs"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1805.12077","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.stat-mech","submitted_at":"2018-05-30T16:50:34Z","cross_cats_sorted":["q-bio.MN"],"title_canon_sha256":"e0d03005a5a8c7fea10313f9f694a26380caa503972a492ff7c60118f0668e84","abstract_canon_sha256":"73b654ee42a14ee4059f8eb28029e232b9ed77d9db0d52d6bd53597990e87c42"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:56:33.876092Z","signature_b64":"jPfSCnkCXRBNvm1lRSYdQTl03u6L1gToA62+VQrKyiJp5TEwzQU8QqTwpQAnUno5HW3EV+xw61LmywswWL/GAA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"e314e502e0fdd028366162403d65509437415f9b7a0f51d30e35430a680ab600","last_reissued_at":"2026-05-17T23:56:33.875418Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:56:33.875418Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Conservation Laws and Work Fluctuation Relations in Chemical Reaction Networks","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.MN"],"primary_cat":"cond-mat.stat-mech","authors_text":"Massimiliano Esposito, Riccardo Rao","submitted_at":"2018-05-30T16:50:34Z","abstract_excerpt":"We formulate a nonequilibrium thermodynamic description for open chemical reaction networks (CRN) described by a chemical master equation. The topological properties of the CRN and its conservation laws are shown to play a crucial role. They are used to decompose the entropy production into a potential change and two work contributions, the first due to time dependent changes in the externally controlled chemostats concentrations and the second due to flows maintained across the system by nonconservative forces. These two works jointly satisfy a Jarzynski and Crooks fluctuation theorem. In abs"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1805.12077","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1805.12077","created_at":"2026-05-17T23:56:33.875524+00:00"},{"alias_kind":"arxiv_version","alias_value":"1805.12077v2","created_at":"2026-05-17T23:56:33.875524+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1805.12077","created_at":"2026-05-17T23:56:33.875524+00:00"},{"alias_kind":"pith_short_12","alias_value":"4MKOKAXA7XIC","created_at":"2026-05-18T12:32:05.422762+00:00"},{"alias_kind":"pith_short_16","alias_value":"4MKOKAXA7XICQNTB","created_at":"2026-05-18T12:32:05.422762+00:00"},{"alias_kind":"pith_short_8","alias_value":"4MKOKAXA","created_at":"2026-05-18T12:32:05.422762+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/4MKOKAXA7XICQNTBMJAD2ZKQSQ","json":"https://pith.science/pith/4MKOKAXA7XICQNTBMJAD2ZKQSQ.json","graph_json":"https://pith.science/api/pith-number/4MKOKAXA7XICQNTBMJAD2ZKQSQ/graph.json","events_json":"https://pith.science/api/pith-number/4MKOKAXA7XICQNTBMJAD2ZKQSQ/events.json","paper":"https://pith.science/paper/4MKOKAXA"},"agent_actions":{"view_html":"https://pith.science/pith/4MKOKAXA7XICQNTBMJAD2ZKQSQ","download_json":"https://pith.science/pith/4MKOKAXA7XICQNTBMJAD2ZKQSQ.json","view_paper":"https://pith.science/paper/4MKOKAXA","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1805.12077&json=true","fetch_graph":"https://pith.science/api/pith-number/4MKOKAXA7XICQNTBMJAD2ZKQSQ/graph.json","fetch_events":"https://pith.science/api/pith-number/4MKOKAXA7XICQNTBMJAD2ZKQSQ/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/4MKOKAXA7XICQNTBMJAD2ZKQSQ/action/timestamp_anchor","attest_storage":"https://pith.science/pith/4MKOKAXA7XICQNTBMJAD2ZKQSQ/action/storage_attestation","attest_author":"https://pith.science/pith/4MKOKAXA7XICQNTBMJAD2ZKQSQ/action/author_attestation","sign_citation":"https://pith.science/pith/4MKOKAXA7XICQNTBMJAD2ZKQSQ/action/citation_signature","submit_replication":"https://pith.science/pith/4MKOKAXA7XICQNTBMJAD2ZKQSQ/action/replication_record"}},"created_at":"2026-05-17T23:56:33.875524+00:00","updated_at":"2026-05-17T23:56:33.875524+00:00"}