{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2013:BMZKPVC4OJJ2DKAJ7UAS6R6CXL","short_pith_number":"pith:BMZKPVC4","canonical_record":{"source":{"id":"1303.0013","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2013-02-28T21:02:36Z","cross_cats_sorted":["q-bio.QM"],"title_canon_sha256":"a9db59ff90741fe632913ff61d20569d306cf1f66cff5bc09fc7232f4f263d4e","abstract_canon_sha256":"91f73a97249d8efe1b91841a25b4f2b98310520f8e90dd68907a49c151d95f4b"},"schema_version":"1.0"},"canonical_sha256":"0b32a7d45c7253a1a809fd012f47c2bad23bac9305b1aa8771a06b589955f91d","source":{"kind":"arxiv","id":"1303.0013","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1303.0013","created_at":"2026-05-18T03:10:36Z"},{"alias_kind":"arxiv_version","alias_value":"1303.0013v2","created_at":"2026-05-18T03:10:36Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1303.0013","created_at":"2026-05-18T03:10:36Z"},{"alias_kind":"pith_short_12","alias_value":"BMZKPVC4OJJ2","created_at":"2026-05-18T12:27:40Z"},{"alias_kind":"pith_short_16","alias_value":"BMZKPVC4OJJ2DKAJ","created_at":"2026-05-18T12:27:40Z"},{"alias_kind":"pith_short_8","alias_value":"BMZKPVC4","created_at":"2026-05-18T12:27:40Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2013:BMZKPVC4OJJ2DKAJ7UAS6R6CXL","target":"record","payload":{"canonical_record":{"source":{"id":"1303.0013","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2013-02-28T21:02:36Z","cross_cats_sorted":["q-bio.QM"],"title_canon_sha256":"a9db59ff90741fe632913ff61d20569d306cf1f66cff5bc09fc7232f4f263d4e","abstract_canon_sha256":"91f73a97249d8efe1b91841a25b4f2b98310520f8e90dd68907a49c151d95f4b"},"schema_version":"1.0"},"canonical_sha256":"0b32a7d45c7253a1a809fd012f47c2bad23bac9305b1aa8771a06b589955f91d","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T03:10:36.969940Z","signature_b64":"qZ6mz9x8QoD6Et6CtaHZAsFq+kaHP31EatT0vZtCtrOA6vvRvVhRwKq+KkjMqDSGo8jrkFLTfktw4zVvpX2gDg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"0b32a7d45c7253a1a809fd012f47c2bad23bac9305b1aa8771a06b589955f91d","last_reissued_at":"2026-05-18T03:10:36.969502Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T03:10:36.969502Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1303.0013","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:10:36Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"T5xLgURbqS53P2/EMOxtOHW4NaqjxxafKj3RJRJsjx6uUtlpMtkp90HIPJ2pvhqD30Umr43fCzerN3UhnWILDg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-31T08:41:05.851988Z"},"content_sha256":"c8eff87f5c3a0f6867e36fc4f720258a0f83529de2a15c1c3acd751c24c843f8","schema_version":"1.0","event_id":"sha256:c8eff87f5c3a0f6867e36fc4f720258a0f83529de2a15c1c3acd751c24c843f8"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2013:BMZKPVC4OJJ2DKAJ7UAS6R6CXL","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Cell-type-specific microarray data and the Allen atlas: quantitative analysis of brain-wide patterns of correlation and density","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.QM"],"primary_cat":"q-bio.NC","authors_text":"Michael Hawrylycz, Partha P. Mitra, Pascal Grange","submitted_at":"2013-02-28T21:02:36Z","abstract_excerpt":"The Allen Atlas of the adult mouse brain is used to estimate the region-specificity of 64 cell types whose transcriptional profile in the mouse brain has been measured in microarray experiments. We systematically analyze the preliminary results presented in [arXiv:1111.6217], using the techniques implemented in the Brain Gene Expression Analysis toolbox. In particular, for each cell-type-specific sample in the study, we compute a brain-wide correlation profile to the Allen Atlas, and estimate a brain-wide density profile by solving a quadratic optimization problem at each voxel in the mouse br"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1303.0013","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:10:36Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"1YLGjDX9heNemkhrtjbnN0lGYKRq7sq4Xzyl90oFG9Av5XZMlIx05c1lPywdBkhIFGTPoiBBfvNp/9UUAUVUDw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-31T08:41:05.852753Z"},"content_sha256":"0624817fac4c17cb27e782931cc32a1458502345f286dc433bd41921065e5da6","schema_version":"1.0","event_id":"sha256:0624817fac4c17cb27e782931cc32a1458502345f286dc433bd41921065e5da6"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/BMZKPVC4OJJ2DKAJ7UAS6R6CXL/bundle.json","state_url":"https://pith.science/pith/BMZKPVC4OJJ2DKAJ7UAS6R6CXL/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/BMZKPVC4OJJ2DKAJ7UAS6R6CXL/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-31T08:41:05Z","links":{"resolver":"https://pith.science/pith/BMZKPVC4OJJ2DKAJ7UAS6R6CXL","bundle":"https://pith.science/pith/BMZKPVC4OJJ2DKAJ7UAS6R6CXL/bundle.json","state":"https://pith.science/pith/BMZKPVC4OJJ2DKAJ7UAS6R6CXL/state.json","well_known_bundle":"https://pith.science/.well-known/pith/BMZKPVC4OJJ2DKAJ7UAS6R6CXL/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2013:BMZKPVC4OJJ2DKAJ7UAS6R6CXL","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"91f73a97249d8efe1b91841a25b4f2b98310520f8e90dd68907a49c151d95f4b","cross_cats_sorted":["q-bio.QM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2013-02-28T21:02:36Z","title_canon_sha256":"a9db59ff90741fe632913ff61d20569d306cf1f66cff5bc09fc7232f4f263d4e"},"schema_version":"1.0","source":{"id":"1303.0013","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1303.0013","created_at":"2026-05-18T03:10:36Z"},{"alias_kind":"arxiv_version","alias_value":"1303.0013v2","created_at":"2026-05-18T03:10:36Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1303.0013","created_at":"2026-05-18T03:10:36Z"},{"alias_kind":"pith_short_12","alias_value":"BMZKPVC4OJJ2","created_at":"2026-05-18T12:27:40Z"},{"alias_kind":"pith_short_16","alias_value":"BMZKPVC4OJJ2DKAJ","created_at":"2026-05-18T12:27:40Z"},{"alias_kind":"pith_short_8","alias_value":"BMZKPVC4","created_at":"2026-05-18T12:27:40Z"}],"graph_snapshots":[{"event_id":"sha256:0624817fac4c17cb27e782931cc32a1458502345f286dc433bd41921065e5da6","target":"graph","created_at":"2026-05-18T03:10:36Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The Allen Atlas of the adult mouse brain is used to estimate the region-specificity of 64 cell types whose transcriptional profile in the mouse brain has been measured in microarray experiments. We systematically analyze the preliminary results presented in [arXiv:1111.6217], using the techniques implemented in the Brain Gene Expression Analysis toolbox. In particular, for each cell-type-specific sample in the study, we compute a brain-wide correlation profile to the Allen Atlas, and estimate a brain-wide density profile by solving a quadratic optimization problem at each voxel in the mouse br","authors_text":"Michael Hawrylycz, Partha P. Mitra, Pascal Grange","cross_cats":["q-bio.QM"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2013-02-28T21:02:36Z","title":"Cell-type-specific microarray data and the Allen atlas: quantitative analysis of brain-wide patterns of correlation and density"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1303.0013","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:c8eff87f5c3a0f6867e36fc4f720258a0f83529de2a15c1c3acd751c24c843f8","target":"record","created_at":"2026-05-18T03:10:36Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"91f73a97249d8efe1b91841a25b4f2b98310520f8e90dd68907a49c151d95f4b","cross_cats_sorted":["q-bio.QM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2013-02-28T21:02:36Z","title_canon_sha256":"a9db59ff90741fe632913ff61d20569d306cf1f66cff5bc09fc7232f4f263d4e"},"schema_version":"1.0","source":{"id":"1303.0013","kind":"arxiv","version":2}},"canonical_sha256":"0b32a7d45c7253a1a809fd012f47c2bad23bac9305b1aa8771a06b589955f91d","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"0b32a7d45c7253a1a809fd012f47c2bad23bac9305b1aa8771a06b589955f91d","first_computed_at":"2026-05-18T03:10:36.969502Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T03:10:36.969502Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"qZ6mz9x8QoD6Et6CtaHZAsFq+kaHP31EatT0vZtCtrOA6vvRvVhRwKq+KkjMqDSGo8jrkFLTfktw4zVvpX2gDg==","signature_status":"signed_v1","signed_at":"2026-05-18T03:10:36.969940Z","signed_message":"canonical_sha256_bytes"},"source_id":"1303.0013","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:c8eff87f5c3a0f6867e36fc4f720258a0f83529de2a15c1c3acd751c24c843f8","sha256:0624817fac4c17cb27e782931cc32a1458502345f286dc433bd41921065e5da6"],"state_sha256":"e7e11a895abc6c39f94e8edd4c31c953d1ec0d4a6a353ffaeb50d33da70cc2b5"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"py4iC01csqNKdBLGCDWH/pRyICPyK281SRDHERbEYyUqfwxkx1H2abeXWIaoRAdgOcwHgM65m6bSzVQgFkdWBA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-31T08:41:05.856823Z","bundle_sha256":"f4f02e3ae580f680bb209e184bdacd443da6b6ea6b36e9fd67216f64fa0cd6ab"}}