{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:C3H63W22RVKKAFUBM57SVJBWH2","short_pith_number":"pith:C3H63W22","canonical_record":{"source":{"id":"1909.01429","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-09-03T20:13:35Z","cross_cats_sorted":["cond-mat.soft"],"title_canon_sha256":"4282020453ee59840ebc8b475a88a11ebd7d9f3e131edf40024c656b2fa5f020","abstract_canon_sha256":"b71a194c4711621cd88ca0e1957576726f52a552906b78fa1dd8c6becc0f1360"},"schema_version":"1.0"},"canonical_sha256":"16cfeddb5a8d54a01681677f2aa4363eb6ab89432138ab8dc48f6901eb2faacb","source":{"kind":"arxiv","id":"1909.01429","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1909.01429","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"arxiv_version","alias_value":"1909.01429v1","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1909.01429","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"pith_short_12","alias_value":"C3H63W22RVKK","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"pith_short_16","alias_value":"C3H63W22RVKKAFUB","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"pith_short_8","alias_value":"C3H63W22","created_at":"2026-07-05T00:02:16Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:C3H63W22RVKKAFUBM57SVJBWH2","target":"record","payload":{"canonical_record":{"source":{"id":"1909.01429","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-09-03T20:13:35Z","cross_cats_sorted":["cond-mat.soft"],"title_canon_sha256":"4282020453ee59840ebc8b475a88a11ebd7d9f3e131edf40024c656b2fa5f020","abstract_canon_sha256":"b71a194c4711621cd88ca0e1957576726f52a552906b78fa1dd8c6becc0f1360"},"schema_version":"1.0"},"canonical_sha256":"16cfeddb5a8d54a01681677f2aa4363eb6ab89432138ab8dc48f6901eb2faacb","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T00:02:16.203677Z","signature_b64":"NDzfesuHnNFEzUD22LlLQGgQVubMq74gw2p5b7yR2LT+SazW7Y9chq7RCDV9OCsQWvDhrxxwpZGQpfg8R0c7DQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"16cfeddb5a8d54a01681677f2aa4363eb6ab89432138ab8dc48f6901eb2faacb","last_reissued_at":"2026-07-05T00:02:16.203231Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T00:02:16.203231Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1909.01429","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T00:02:16Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"sKJKi5wzARca1NaPE7wWlkuurwqBrBcY6aR+JoldAkU1oY9qtaZL4c2tuxuoKXVgWK7MPKuL3qnBv9fMoEcxBg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-06T08:28:52.320436Z"},"content_sha256":"76e8c43c154ad49236c2d83c022a4400d8c4c09831049d493282dac39a475566","schema_version":"1.0","event_id":"sha256:76e8c43c154ad49236c2d83c022a4400d8c4c09831049d493282dac39a475566"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:C3H63W22RVKKAFUBM57SVJBWH2","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Statistical physics and mesoscopic modeling to interpret tethered particle motion experiments","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft"],"primary_cat":"physics.bio-ph","authors_text":"Anna\\\"el Brunet, Manoel Manghi, Nicolas Destainville","submitted_at":"2019-09-03T20:13:35Z","abstract_excerpt":"Tethered particle motion experiments are versatile single-molecule techniques enabling one to address in vitro the molecular properties of DNA and its interactions with various partners involved in genetic regulations. These techniques provide raw data such as the tracked particle amplitude of movement, from which relevant information about DNA conformations or states must be recovered. Solving this inverse problem appeals to specific theoretical tools that have been designed in the two last decades, together with the data pre-processing procedures that ought to be implemented to avoid biases "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1909.01429","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/1909.01429/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T00:02:16Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"pV8mu8aApDHmqTEaeEL2FtGldcst+5ZSTQZXXAYA2EPBQsMf3j9/xgw/jNGPKm1xBZG7xPu0BylKWLWgj3yVCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-06T08:28:52.320814Z"},"content_sha256":"a28c8ede0c2373188a09134514dc20d2c0d58489f42b424a34aad099c5498783","schema_version":"1.0","event_id":"sha256:a28c8ede0c2373188a09134514dc20d2c0d58489f42b424a34aad099c5498783"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/C3H63W22RVKKAFUBM57SVJBWH2/bundle.json","state_url":"https://pith.science/pith/C3H63W22RVKKAFUBM57SVJBWH2/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/C3H63W22RVKKAFUBM57SVJBWH2/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-06T08:28:52Z","links":{"resolver":"https://pith.science/pith/C3H63W22RVKKAFUBM57SVJBWH2","bundle":"https://pith.science/pith/C3H63W22RVKKAFUBM57SVJBWH2/bundle.json","state":"https://pith.science/pith/C3H63W22RVKKAFUBM57SVJBWH2/state.json","well_known_bundle":"https://pith.science/.well-known/pith/C3H63W22RVKKAFUBM57SVJBWH2/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:C3H63W22RVKKAFUBM57SVJBWH2","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"b71a194c4711621cd88ca0e1957576726f52a552906b78fa1dd8c6becc0f1360","cross_cats_sorted":["cond-mat.soft"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-09-03T20:13:35Z","title_canon_sha256":"4282020453ee59840ebc8b475a88a11ebd7d9f3e131edf40024c656b2fa5f020"},"schema_version":"1.0","source":{"id":"1909.01429","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1909.01429","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"arxiv_version","alias_value":"1909.01429v1","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1909.01429","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"pith_short_12","alias_value":"C3H63W22RVKK","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"pith_short_16","alias_value":"C3H63W22RVKKAFUB","created_at":"2026-07-05T00:02:16Z"},{"alias_kind":"pith_short_8","alias_value":"C3H63W22","created_at":"2026-07-05T00:02:16Z"}],"graph_snapshots":[{"event_id":"sha256:a28c8ede0c2373188a09134514dc20d2c0d58489f42b424a34aad099c5498783","target":"graph","created_at":"2026-07-05T00:02:16Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/1909.01429/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Tethered particle motion experiments are versatile single-molecule techniques enabling one to address in vitro the molecular properties of DNA and its interactions with various partners involved in genetic regulations. These techniques provide raw data such as the tracked particle amplitude of movement, from which relevant information about DNA conformations or states must be recovered. Solving this inverse problem appeals to specific theoretical tools that have been designed in the two last decades, together with the data pre-processing procedures that ought to be implemented to avoid biases ","authors_text":"Anna\\\"el Brunet, Manoel Manghi, Nicolas Destainville","cross_cats":["cond-mat.soft"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-09-03T20:13:35Z","title":"Statistical physics and mesoscopic modeling to interpret tethered particle motion experiments"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1909.01429","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:76e8c43c154ad49236c2d83c022a4400d8c4c09831049d493282dac39a475566","target":"record","created_at":"2026-07-05T00:02:16Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"b71a194c4711621cd88ca0e1957576726f52a552906b78fa1dd8c6becc0f1360","cross_cats_sorted":["cond-mat.soft"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-09-03T20:13:35Z","title_canon_sha256":"4282020453ee59840ebc8b475a88a11ebd7d9f3e131edf40024c656b2fa5f020"},"schema_version":"1.0","source":{"id":"1909.01429","kind":"arxiv","version":1}},"canonical_sha256":"16cfeddb5a8d54a01681677f2aa4363eb6ab89432138ab8dc48f6901eb2faacb","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"16cfeddb5a8d54a01681677f2aa4363eb6ab89432138ab8dc48f6901eb2faacb","first_computed_at":"2026-07-05T00:02:16.203231Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T00:02:16.203231Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"NDzfesuHnNFEzUD22LlLQGgQVubMq74gw2p5b7yR2LT+SazW7Y9chq7RCDV9OCsQWvDhrxxwpZGQpfg8R0c7DQ==","signature_status":"signed_v1","signed_at":"2026-07-05T00:02:16.203677Z","signed_message":"canonical_sha256_bytes"},"source_id":"1909.01429","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:76e8c43c154ad49236c2d83c022a4400d8c4c09831049d493282dac39a475566","sha256:a28c8ede0c2373188a09134514dc20d2c0d58489f42b424a34aad099c5498783"],"state_sha256":"72c6c723742490cfcf40e8ea6a02ab204a5e26a334177af8a1ea37dfdaec0494"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"TWwiqTmfv2kaxtd3DDRUxiY11nURuj3OI82QGfU+KC/fyoJP+nHE8cY2ZDkJImjSE094VxQ94IGVxgkd/9LxDw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-06T08:28:52.322872Z","bundle_sha256":"2fb2a918827670a6a8b2260b0bfd1ff070fb4818592d1b060620a7c958f3e5c5"}}