{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2016:CV6L5XBTYMFQ7R37SBH3U4JVIX","short_pith_number":"pith:CV6L5XBT","schema_version":"1.0","canonical_sha256":"157cbedc33c30b0fc77f904fba713545c759670711bdac1d8292226f5c027de1","source":{"kind":"arxiv","id":"1609.08205","version":1},"attestation_state":"computed","paper":{"title":"Random-phase-approximation theory for sequence-dependent, biologically functional liquid-liquid phase separation of intrinsically disordered proteins","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft"],"primary_cat":"q-bio.BM","authors_text":"Hue Sun Chan, Jianhui Song, Julie D. Forman-Kay, Yi-Hsuan Lin","submitted_at":"2016-09-26T22:02:35Z","abstract_excerpt":"Intrinsically disordered proteins (IDPs) are typically low in nonpolar/hydrophobic but relatively high in polar, charged, and aromatic amino acid compositions. Some IDPs undergo liquid-liquid phase separation in the aqueous milieu of the living cell. The resulting phase with enhanced IDP concentration can function as a major component of membraneless organelles that, by creating their own IDP-rich microenvironments, stimulate critical biological functions. IDP phase behaviors are governed by their amino acid sequences. To make progress in understanding this sequence-phase relationship, we repo"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1609.08205","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2016-09-26T22:02:35Z","cross_cats_sorted":["cond-mat.soft"],"title_canon_sha256":"52bcb5224a364c54f4a907a88265420e6b254381a1e0b0cf3063a09165e7020e","abstract_canon_sha256":"c41d18db838d4b477e102d6c71aa85b11c2f808ec1fd21ac87c91a8c5b15dbdf"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:44:15.882247Z","signature_b64":"DnDCNQJeQTbebM+airhMGh8LfRc7UOEHUyY6lbeGv3hNfhGqD7o4nnQcfFCsVt4Jz6JYJSXlPnj3lHZaS227Cg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"157cbedc33c30b0fc77f904fba713545c759670711bdac1d8292226f5c027de1","last_reissued_at":"2026-05-18T00:44:15.881558Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:44:15.881558Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Random-phase-approximation theory for sequence-dependent, biologically functional liquid-liquid phase separation of intrinsically disordered proteins","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft"],"primary_cat":"q-bio.BM","authors_text":"Hue Sun Chan, Jianhui Song, Julie D. Forman-Kay, Yi-Hsuan Lin","submitted_at":"2016-09-26T22:02:35Z","abstract_excerpt":"Intrinsically disordered proteins (IDPs) are typically low in nonpolar/hydrophobic but relatively high in polar, charged, and aromatic amino acid compositions. Some IDPs undergo liquid-liquid phase separation in the aqueous milieu of the living cell. The resulting phase with enhanced IDP concentration can function as a major component of membraneless organelles that, by creating their own IDP-rich microenvironments, stimulate critical biological functions. IDP phase behaviors are governed by their amino acid sequences. To make progress in understanding this sequence-phase relationship, we repo"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1609.08205","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1609.08205","created_at":"2026-05-18T00:44:15.881654+00:00"},{"alias_kind":"arxiv_version","alias_value":"1609.08205v1","created_at":"2026-05-18T00:44:15.881654+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1609.08205","created_at":"2026-05-18T00:44:15.881654+00:00"},{"alias_kind":"pith_short_12","alias_value":"CV6L5XBTYMFQ","created_at":"2026-05-18T12:30:09.641336+00:00"},{"alias_kind":"pith_short_16","alias_value":"CV6L5XBTYMFQ7R37","created_at":"2026-05-18T12:30:09.641336+00:00"},{"alias_kind":"pith_short_8","alias_value":"CV6L5XBT","created_at":"2026-05-18T12:30:09.641336+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/CV6L5XBTYMFQ7R37SBH3U4JVIX","json":"https://pith.science/pith/CV6L5XBTYMFQ7R37SBH3U4JVIX.json","graph_json":"https://pith.science/api/pith-number/CV6L5XBTYMFQ7R37SBH3U4JVIX/graph.json","events_json":"https://pith.science/api/pith-number/CV6L5XBTYMFQ7R37SBH3U4JVIX/events.json","paper":"https://pith.science/paper/CV6L5XBT"},"agent_actions":{"view_html":"https://pith.science/pith/CV6L5XBTYMFQ7R37SBH3U4JVIX","download_json":"https://pith.science/pith/CV6L5XBTYMFQ7R37SBH3U4JVIX.json","view_paper":"https://pith.science/paper/CV6L5XBT","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1609.08205&json=true","fetch_graph":"https://pith.science/api/pith-number/CV6L5XBTYMFQ7R37SBH3U4JVIX/graph.json","fetch_events":"https://pith.science/api/pith-number/CV6L5XBTYMFQ7R37SBH3U4JVIX/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/CV6L5XBTYMFQ7R37SBH3U4JVIX/action/timestamp_anchor","attest_storage":"https://pith.science/pith/CV6L5XBTYMFQ7R37SBH3U4JVIX/action/storage_attestation","attest_author":"https://pith.science/pith/CV6L5XBTYMFQ7R37SBH3U4JVIX/action/author_attestation","sign_citation":"https://pith.science/pith/CV6L5XBTYMFQ7R37SBH3U4JVIX/action/citation_signature","submit_replication":"https://pith.science/pith/CV6L5XBTYMFQ7R37SBH3U4JVIX/action/replication_record"}},"created_at":"2026-05-18T00:44:15.881654+00:00","updated_at":"2026-05-18T00:44:15.881654+00:00"}