{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:K4VKINMRKP6ROT27XBG3MRA6JK","short_pith_number":"pith:K4VKINMR","canonical_record":{"source":{"id":"1804.00813","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2018-04-03T04:02:28Z","cross_cats_sorted":["physics.bio-ph","q-bio.SC"],"title_canon_sha256":"a352ebe3452764004ffe6d2e0611543a4b91710cd80677f65b37382c117f2bcf","abstract_canon_sha256":"c1d456e6e88862c2c63096f69cf01f425aaa3625c364470ce0f80ed254003af5"},"schema_version":"1.0"},"canonical_sha256":"572aa4359153fd174f5fb84db6441e4ab1cea51851f9b01627a105da5cb479ef","source":{"kind":"arxiv","id":"1804.00813","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1804.00813","created_at":"2026-05-18T00:19:32Z"},{"alias_kind":"arxiv_version","alias_value":"1804.00813v1","created_at":"2026-05-18T00:19:32Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1804.00813","created_at":"2026-05-18T00:19:32Z"},{"alias_kind":"pith_short_12","alias_value":"K4VKINMRKP6R","created_at":"2026-05-18T12:32:33Z"},{"alias_kind":"pith_short_16","alias_value":"K4VKINMRKP6ROT27","created_at":"2026-05-18T12:32:33Z"},{"alias_kind":"pith_short_8","alias_value":"K4VKINMR","created_at":"2026-05-18T12:32:33Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:K4VKINMRKP6ROT27XBG3MRA6JK","target":"record","payload":{"canonical_record":{"source":{"id":"1804.00813","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2018-04-03T04:02:28Z","cross_cats_sorted":["physics.bio-ph","q-bio.SC"],"title_canon_sha256":"a352ebe3452764004ffe6d2e0611543a4b91710cd80677f65b37382c117f2bcf","abstract_canon_sha256":"c1d456e6e88862c2c63096f69cf01f425aaa3625c364470ce0f80ed254003af5"},"schema_version":"1.0"},"canonical_sha256":"572aa4359153fd174f5fb84db6441e4ab1cea51851f9b01627a105da5cb479ef","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:19:32.072127Z","signature_b64":"ZjvWwiWe5knhRDGP03D46DI68UmzWz3yxbZVyeR8h2klm3oZxUkalRuc784oT8HHZjSHc6yqIEcB9sDjmoI1Ag==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"572aa4359153fd174f5fb84db6441e4ab1cea51851f9b01627a105da5cb479ef","last_reissued_at":"2026-05-18T00:19:32.071276Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:19:32.071276Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1804.00813","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:19:32Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"jvB+f90IymqzrcR7useExtYLFpd56bH4BcF26eClgVddf/XOPcMOp+b/9Sv+Ab5voLvjoeB+KOpbXS/aKFpKCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-22T05:59:24.491961Z"},"content_sha256":"ab1360515bf354f95cdd08dfeff35ab8f0d7c7b98b9ebdb9c59ab646adeaf187","schema_version":"1.0","event_id":"sha256:ab1360515bf354f95cdd08dfeff35ab8f0d7c7b98b9ebdb9c59ab646adeaf187"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:K4VKINMRKP6ROT27XBG3MRA6JK","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Large-scale chirality in an active layer of microtubules and kinesin motor proteins","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph","q-bio.SC"],"primary_cat":"cond-mat.soft","authors_text":"Hikaru Nakazawa, Kyongwan Kim, Mitsuo Umetsu, Natsuhiko Yoshinaga, Sanjib Bhattacharyya, Winfried Teizer","submitted_at":"2018-04-03T04:02:28Z","abstract_excerpt":"During the early developmental process of organisms, the formation of the left-right laterality requires a subtle mechanism, as it is associated with other principal body axes. Any inherent chiral feature in an egg cell can in principal trigger this spontaneous breaking of chiral symmetry. Individual microtubules, major cytoskeletal filaments, are known as chiral objects. However, to date there lacks convincing evidence of a hierarchical connection of the molecular nature of microtubules to large-scale chirality, particularly at the length scale of an entire cell. Here we assemble an in-vitro "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1804.00813","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:19:32Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"qJmM1JMFc8BPi/W/vHdP9VraunBTAB2LGspP1wUYlnrssH1NlGU0wjsdMPNyUG7U7ySwSi1inYh44KtBIXMMDw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-22T05:59:24.492309Z"},"content_sha256":"2de085e1bda6e72d4b44960f55c3e70d67069be7aa216bf7ab67d7950532b1a9","schema_version":"1.0","event_id":"sha256:2de085e1bda6e72d4b44960f55c3e70d67069be7aa216bf7ab67d7950532b1a9"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/K4VKINMRKP6ROT27XBG3MRA6JK/bundle.json","state_url":"https://pith.science/pith/K4VKINMRKP6ROT27XBG3MRA6JK/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/K4VKINMRKP6ROT27XBG3MRA6JK/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-22T05:59:24Z","links":{"resolver":"https://pith.science/pith/K4VKINMRKP6ROT27XBG3MRA6JK","bundle":"https://pith.science/pith/K4VKINMRKP6ROT27XBG3MRA6JK/bundle.json","state":"https://pith.science/pith/K4VKINMRKP6ROT27XBG3MRA6JK/state.json","well_known_bundle":"https://pith.science/.well-known/pith/K4VKINMRKP6ROT27XBG3MRA6JK/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:K4VKINMRKP6ROT27XBG3MRA6JK","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"c1d456e6e88862c2c63096f69cf01f425aaa3625c364470ce0f80ed254003af5","cross_cats_sorted":["physics.bio-ph","q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2018-04-03T04:02:28Z","title_canon_sha256":"a352ebe3452764004ffe6d2e0611543a4b91710cd80677f65b37382c117f2bcf"},"schema_version":"1.0","source":{"id":"1804.00813","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1804.00813","created_at":"2026-05-18T00:19:32Z"},{"alias_kind":"arxiv_version","alias_value":"1804.00813v1","created_at":"2026-05-18T00:19:32Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1804.00813","created_at":"2026-05-18T00:19:32Z"},{"alias_kind":"pith_short_12","alias_value":"K4VKINMRKP6R","created_at":"2026-05-18T12:32:33Z"},{"alias_kind":"pith_short_16","alias_value":"K4VKINMRKP6ROT27","created_at":"2026-05-18T12:32:33Z"},{"alias_kind":"pith_short_8","alias_value":"K4VKINMR","created_at":"2026-05-18T12:32:33Z"}],"graph_snapshots":[{"event_id":"sha256:2de085e1bda6e72d4b44960f55c3e70d67069be7aa216bf7ab67d7950532b1a9","target":"graph","created_at":"2026-05-18T00:19:32Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"During the early developmental process of organisms, the formation of the left-right laterality requires a subtle mechanism, as it is associated with other principal body axes. Any inherent chiral feature in an egg cell can in principal trigger this spontaneous breaking of chiral symmetry. Individual microtubules, major cytoskeletal filaments, are known as chiral objects. However, to date there lacks convincing evidence of a hierarchical connection of the molecular nature of microtubules to large-scale chirality, particularly at the length scale of an entire cell. Here we assemble an in-vitro ","authors_text":"Hikaru Nakazawa, Kyongwan Kim, Mitsuo Umetsu, Natsuhiko Yoshinaga, Sanjib Bhattacharyya, Winfried Teizer","cross_cats":["physics.bio-ph","q-bio.SC"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2018-04-03T04:02:28Z","title":"Large-scale chirality in an active layer of microtubules and kinesin motor proteins"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1804.00813","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:ab1360515bf354f95cdd08dfeff35ab8f0d7c7b98b9ebdb9c59ab646adeaf187","target":"record","created_at":"2026-05-18T00:19:32Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"c1d456e6e88862c2c63096f69cf01f425aaa3625c364470ce0f80ed254003af5","cross_cats_sorted":["physics.bio-ph","q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2018-04-03T04:02:28Z","title_canon_sha256":"a352ebe3452764004ffe6d2e0611543a4b91710cd80677f65b37382c117f2bcf"},"schema_version":"1.0","source":{"id":"1804.00813","kind":"arxiv","version":1}},"canonical_sha256":"572aa4359153fd174f5fb84db6441e4ab1cea51851f9b01627a105da5cb479ef","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"572aa4359153fd174f5fb84db6441e4ab1cea51851f9b01627a105da5cb479ef","first_computed_at":"2026-05-18T00:19:32.071276Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:19:32.071276Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"ZjvWwiWe5knhRDGP03D46DI68UmzWz3yxbZVyeR8h2klm3oZxUkalRuc784oT8HHZjSHc6yqIEcB9sDjmoI1Ag==","signature_status":"signed_v1","signed_at":"2026-05-18T00:19:32.072127Z","signed_message":"canonical_sha256_bytes"},"source_id":"1804.00813","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:ab1360515bf354f95cdd08dfeff35ab8f0d7c7b98b9ebdb9c59ab646adeaf187","sha256:2de085e1bda6e72d4b44960f55c3e70d67069be7aa216bf7ab67d7950532b1a9"],"state_sha256":"3a34e6bbdfd99780fbc91a7baf079076e04c9edacb5b195ab7a70d25b51fd0a9"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"d7viPtae9Fi9OGaoef8jA8IiXRr3PdFW7p3agXuLYHWnCzeab2XdiraNrG0igE5bf3BGH/wiBVhUbOPRX0LbCA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-22T05:59:24.494419Z","bundle_sha256":"37816ad2d23012d889a729d4df2d6862dedc94e6c7e9b5c2b9f9cae941a1407f"}}