{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2012:KVFZSMRRTHIK7GG6PTVEH76QVA","short_pith_number":"pith:KVFZSMRR","canonical_record":{"source":{"id":"1201.2779","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.TO","submitted_at":"2012-01-13T09:34:26Z","cross_cats_sorted":["cond-mat.soft","physics.bio-ph","q-bio.CB"],"title_canon_sha256":"9ba1492bf5f0d0f9efe86af123f94eaceeb618d28033078a3a9917d15dadc980","abstract_canon_sha256":"bcc702c11ec8bae9b15f3c399a3a83e4fdcef2897d20073cdf667efc7dc612d8"},"schema_version":"1.0"},"canonical_sha256":"554b99323199d0af98de7cea43ffd0a8028d57b221805a51acb9553a450da838","source":{"kind":"arxiv","id":"1201.2779","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1201.2779","created_at":"2026-05-18T04:04:43Z"},{"alias_kind":"arxiv_version","alias_value":"1201.2779v1","created_at":"2026-05-18T04:04:43Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1201.2779","created_at":"2026-05-18T04:04:43Z"},{"alias_kind":"pith_short_12","alias_value":"KVFZSMRRTHIK","created_at":"2026-05-18T12:27:11Z"},{"alias_kind":"pith_short_16","alias_value":"KVFZSMRRTHIK7GG6","created_at":"2026-05-18T12:27:11Z"},{"alias_kind":"pith_short_8","alias_value":"KVFZSMRR","created_at":"2026-05-18T12:27:11Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2012:KVFZSMRRTHIK7GG6PTVEH76QVA","target":"record","payload":{"canonical_record":{"source":{"id":"1201.2779","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.TO","submitted_at":"2012-01-13T09:34:26Z","cross_cats_sorted":["cond-mat.soft","physics.bio-ph","q-bio.CB"],"title_canon_sha256":"9ba1492bf5f0d0f9efe86af123f94eaceeb618d28033078a3a9917d15dadc980","abstract_canon_sha256":"bcc702c11ec8bae9b15f3c399a3a83e4fdcef2897d20073cdf667efc7dc612d8"},"schema_version":"1.0"},"canonical_sha256":"554b99323199d0af98de7cea43ffd0a8028d57b221805a51acb9553a450da838","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T04:04:43.129915Z","signature_b64":"s8G7mWX/egDW/NzS697taqsUKMTrEudUGBnjp0vUSvbOFSDGTjKUvwjyDMyiJHhmC6XunuHm7oGked3LpedQDg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"554b99323199d0af98de7cea43ffd0a8028d57b221805a51acb9553a450da838","last_reissued_at":"2026-05-18T04:04:43.129451Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T04:04:43.129451Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1201.2779","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:04:43Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"1KQqvGp8MOnw1KS51eX/VbMBVWH7H8fV8J0dN8PPOo73wfEEQK5ht7aYaUtb/i3zzutLPCdRii0F6Ze63/3CCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-24T23:38:03.372750Z"},"content_sha256":"35742b58695573f2a66b2e82226e53c1ba9a56fd7f954b0c71e7e32d981512c6","schema_version":"1.0","event_id":"sha256:35742b58695573f2a66b2e82226e53c1ba9a56fd7f954b0c71e7e32d981512c6"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2012:KVFZSMRRTHIK7GG6PTVEH76QVA","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Force localization in contracting cell layers","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft","physics.bio-ph","q-bio.CB"],"primary_cat":"q-bio.TO","authors_text":"Carina M. Edwards, Ulrich S. Schwarz (U Heidelberg)","submitted_at":"2012-01-13T09:34:26Z","abstract_excerpt":"Epithelial cell layers on soft elastic substrates or pillar arrays are commonly used as model systems for investigating the role of force in tissue growth, maintenance and repair. Here we show analytically that the experimentally observed localization of traction forces to the periphery of the cell layers does not necessarily imply increased local cell activity, but follows naturally from the elastic problem of a finite-sized contractile layer coupled to an elastic foundation. For homogeneous contractility, the force localization is determined by one dimensionless parameter interpolating betwe"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1201.2779","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:04:43Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"EC3UEodA57I3SHRaXQgy/yaodJuoFkDlmDEvAKQdp4p9Jp8APd+uS/ILTs7f46RdHR6qZXgBsQNSeDmFHux+CA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-24T23:38:03.373214Z"},"content_sha256":"3be3a20862c98861c918da78579948ae0c62055ecd7c592102363529f630f411","schema_version":"1.0","event_id":"sha256:3be3a20862c98861c918da78579948ae0c62055ecd7c592102363529f630f411"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/KVFZSMRRTHIK7GG6PTVEH76QVA/bundle.json","state_url":"https://pith.science/pith/KVFZSMRRTHIK7GG6PTVEH76QVA/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/KVFZSMRRTHIK7GG6PTVEH76QVA/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-24T23:38:03Z","links":{"resolver":"https://pith.science/pith/KVFZSMRRTHIK7GG6PTVEH76QVA","bundle":"https://pith.science/pith/KVFZSMRRTHIK7GG6PTVEH76QVA/bundle.json","state":"https://pith.science/pith/KVFZSMRRTHIK7GG6PTVEH76QVA/state.json","well_known_bundle":"https://pith.science/.well-known/pith/KVFZSMRRTHIK7GG6PTVEH76QVA/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2012:KVFZSMRRTHIK7GG6PTVEH76QVA","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"bcc702c11ec8bae9b15f3c399a3a83e4fdcef2897d20073cdf667efc7dc612d8","cross_cats_sorted":["cond-mat.soft","physics.bio-ph","q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.TO","submitted_at":"2012-01-13T09:34:26Z","title_canon_sha256":"9ba1492bf5f0d0f9efe86af123f94eaceeb618d28033078a3a9917d15dadc980"},"schema_version":"1.0","source":{"id":"1201.2779","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1201.2779","created_at":"2026-05-18T04:04:43Z"},{"alias_kind":"arxiv_version","alias_value":"1201.2779v1","created_at":"2026-05-18T04:04:43Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1201.2779","created_at":"2026-05-18T04:04:43Z"},{"alias_kind":"pith_short_12","alias_value":"KVFZSMRRTHIK","created_at":"2026-05-18T12:27:11Z"},{"alias_kind":"pith_short_16","alias_value":"KVFZSMRRTHIK7GG6","created_at":"2026-05-18T12:27:11Z"},{"alias_kind":"pith_short_8","alias_value":"KVFZSMRR","created_at":"2026-05-18T12:27:11Z"}],"graph_snapshots":[{"event_id":"sha256:3be3a20862c98861c918da78579948ae0c62055ecd7c592102363529f630f411","target":"graph","created_at":"2026-05-18T04:04:43Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Epithelial cell layers on soft elastic substrates or pillar arrays are commonly used as model systems for investigating the role of force in tissue growth, maintenance and repair. Here we show analytically that the experimentally observed localization of traction forces to the periphery of the cell layers does not necessarily imply increased local cell activity, but follows naturally from the elastic problem of a finite-sized contractile layer coupled to an elastic foundation. For homogeneous contractility, the force localization is determined by one dimensionless parameter interpolating betwe","authors_text":"Carina M. Edwards, Ulrich S. Schwarz (U Heidelberg)","cross_cats":["cond-mat.soft","physics.bio-ph","q-bio.CB"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.TO","submitted_at":"2012-01-13T09:34:26Z","title":"Force localization in contracting cell layers"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1201.2779","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:35742b58695573f2a66b2e82226e53c1ba9a56fd7f954b0c71e7e32d981512c6","target":"record","created_at":"2026-05-18T04:04:43Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"bcc702c11ec8bae9b15f3c399a3a83e4fdcef2897d20073cdf667efc7dc612d8","cross_cats_sorted":["cond-mat.soft","physics.bio-ph","q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.TO","submitted_at":"2012-01-13T09:34:26Z","title_canon_sha256":"9ba1492bf5f0d0f9efe86af123f94eaceeb618d28033078a3a9917d15dadc980"},"schema_version":"1.0","source":{"id":"1201.2779","kind":"arxiv","version":1}},"canonical_sha256":"554b99323199d0af98de7cea43ffd0a8028d57b221805a51acb9553a450da838","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"554b99323199d0af98de7cea43ffd0a8028d57b221805a51acb9553a450da838","first_computed_at":"2026-05-18T04:04:43.129451Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T04:04:43.129451Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"s8G7mWX/egDW/NzS697taqsUKMTrEudUGBnjp0vUSvbOFSDGTjKUvwjyDMyiJHhmC6XunuHm7oGked3LpedQDg==","signature_status":"signed_v1","signed_at":"2026-05-18T04:04:43.129915Z","signed_message":"canonical_sha256_bytes"},"source_id":"1201.2779","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:35742b58695573f2a66b2e82226e53c1ba9a56fd7f954b0c71e7e32d981512c6","sha256:3be3a20862c98861c918da78579948ae0c62055ecd7c592102363529f630f411"],"state_sha256":"260f5b717c2c0ee9ce7e915efd82f18581eb359e589fdad772a34ff43280743c"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"604054q1UdlO6p6DMmEUur3kguKQy1dMcmDPEW/f7LLKV7fUjNINPM+90ylGLEjdNHUfkTtAp+RvSikXLSkqBw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-24T23:38:03.386905Z","bundle_sha256":"9344d4d53aeb0edc1857e56e82255398687acb134fed2244bb58b13d6f3480e0"}}