{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:M4PH7TYHWHDBYQRWX5NKTKR2WT","short_pith_number":"pith:M4PH7TYH","canonical_record":{"source":{"id":"1605.09230","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-05-30T13:42:04Z","cross_cats_sorted":["q-bio.SC"],"title_canon_sha256":"8358fd5c9c80d7264b7fe0bb37c006c7509a542ea3f10f244acdf9b36f5528c5","abstract_canon_sha256":"5e52be85a11c5b0bac483cf21caf149e74e6a140ee1b091b81b0d8ef29e81d03"},"schema_version":"1.0"},"canonical_sha256":"671e7fcf07b1c61c4236bf5aa9aa3ab4e8671d355a2a2e47dfacf81169ff0db6","source":{"kind":"arxiv","id":"1605.09230","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1605.09230","created_at":"2026-05-18T00:57:04Z"},{"alias_kind":"arxiv_version","alias_value":"1605.09230v2","created_at":"2026-05-18T00:57:04Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1605.09230","created_at":"2026-05-18T00:57:04Z"},{"alias_kind":"pith_short_12","alias_value":"M4PH7TYHWHDB","created_at":"2026-05-18T12:30:29Z"},{"alias_kind":"pith_short_16","alias_value":"M4PH7TYHWHDBYQRW","created_at":"2026-05-18T12:30:29Z"},{"alias_kind":"pith_short_8","alias_value":"M4PH7TYH","created_at":"2026-05-18T12:30:29Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:M4PH7TYHWHDBYQRWX5NKTKR2WT","target":"record","payload":{"canonical_record":{"source":{"id":"1605.09230","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-05-30T13:42:04Z","cross_cats_sorted":["q-bio.SC"],"title_canon_sha256":"8358fd5c9c80d7264b7fe0bb37c006c7509a542ea3f10f244acdf9b36f5528c5","abstract_canon_sha256":"5e52be85a11c5b0bac483cf21caf149e74e6a140ee1b091b81b0d8ef29e81d03"},"schema_version":"1.0"},"canonical_sha256":"671e7fcf07b1c61c4236bf5aa9aa3ab4e8671d355a2a2e47dfacf81169ff0db6","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:57:04.427138Z","signature_b64":"LJ41nDZw4/05gPf9lapplnO5pJLW/lf86d6xC3/0KPJPnbMyeFvm2lN594n4W4cL3M7KDT8RrY90oKgtXwU/BA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"671e7fcf07b1c61c4236bf5aa9aa3ab4e8671d355a2a2e47dfacf81169ff0db6","last_reissued_at":"2026-05-18T00:57:04.426493Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:57:04.426493Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1605.09230","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:57:04Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"JVtA5u6HS2KVobBQ4YR/v/DEHH4YDsWfcFmvZsQPQZiBAKvNHdtEOJdaG1cWS4YHlrahJtIetRF0uuX+63K8BA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-23T14:12:53.061352Z"},"content_sha256":"84a1b64f0429871173b2c90af921fa7476ac8f542a5afe508c7b3fb31f1c6c89","schema_version":"1.0","event_id":"sha256:84a1b64f0429871173b2c90af921fa7476ac8f542a5afe508c7b3fb31f1c6c89"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:M4PH7TYHWHDBYQRWX5NKTKR2WT","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.SC"],"primary_cat":"physics.bio-ph","authors_text":"Anne E. Hafner, Heiko Rieger","submitted_at":"2016-05-30T13:42:04Z","abstract_excerpt":"Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal filaments. The transport efficiency is strongly affected by the spatial organization of the cytoskeleton, which constitutes an inhomogeneous, complex network. In cells with a centrosome microtubules grow radially from the central microtubule organizing center towards the cell periphery whereas actin filaments form a dense meshwork, the actin cor"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1605.09230","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:57:04Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"QZfeaUeu4x6Cmux0lfNUkubTvlgtYvCleE7QSFB8xME1KENbFvzSDe8+02roqwKSKLnmoqc645srGUtBBgqGBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-23T14:12:53.061698Z"},"content_sha256":"b37cfe8eaf5536a75e223d34709ac8ae1c71c8eeb5911ad93b09e3edc5220692","schema_version":"1.0","event_id":"sha256:b37cfe8eaf5536a75e223d34709ac8ae1c71c8eeb5911ad93b09e3edc5220692"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/M4PH7TYHWHDBYQRWX5NKTKR2WT/bundle.json","state_url":"https://pith.science/pith/M4PH7TYHWHDBYQRWX5NKTKR2WT/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/M4PH7TYHWHDBYQRWX5NKTKR2WT/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-23T14:12:53Z","links":{"resolver":"https://pith.science/pith/M4PH7TYHWHDBYQRWX5NKTKR2WT","bundle":"https://pith.science/pith/M4PH7TYHWHDBYQRWX5NKTKR2WT/bundle.json","state":"https://pith.science/pith/M4PH7TYHWHDBYQRWX5NKTKR2WT/state.json","well_known_bundle":"https://pith.science/.well-known/pith/M4PH7TYHWHDBYQRWX5NKTKR2WT/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:M4PH7TYHWHDBYQRWX5NKTKR2WT","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"5e52be85a11c5b0bac483cf21caf149e74e6a140ee1b091b81b0d8ef29e81d03","cross_cats_sorted":["q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-05-30T13:42:04Z","title_canon_sha256":"8358fd5c9c80d7264b7fe0bb37c006c7509a542ea3f10f244acdf9b36f5528c5"},"schema_version":"1.0","source":{"id":"1605.09230","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1605.09230","created_at":"2026-05-18T00:57:04Z"},{"alias_kind":"arxiv_version","alias_value":"1605.09230v2","created_at":"2026-05-18T00:57:04Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1605.09230","created_at":"2026-05-18T00:57:04Z"},{"alias_kind":"pith_short_12","alias_value":"M4PH7TYHWHDB","created_at":"2026-05-18T12:30:29Z"},{"alias_kind":"pith_short_16","alias_value":"M4PH7TYHWHDBYQRW","created_at":"2026-05-18T12:30:29Z"},{"alias_kind":"pith_short_8","alias_value":"M4PH7TYH","created_at":"2026-05-18T12:30:29Z"}],"graph_snapshots":[{"event_id":"sha256:b37cfe8eaf5536a75e223d34709ac8ae1c71c8eeb5911ad93b09e3edc5220692","target":"graph","created_at":"2026-05-18T00:57:04Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal filaments. The transport efficiency is strongly affected by the spatial organization of the cytoskeleton, which constitutes an inhomogeneous, complex network. In cells with a centrosome microtubules grow radially from the central microtubule organizing center towards the cell periphery whereas actin filaments form a dense meshwork, the actin cor","authors_text":"Anne E. Hafner, Heiko Rieger","cross_cats":["q-bio.SC"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-05-30T13:42:04Z","title":"Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1605.09230","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:84a1b64f0429871173b2c90af921fa7476ac8f542a5afe508c7b3fb31f1c6c89","target":"record","created_at":"2026-05-18T00:57:04Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"5e52be85a11c5b0bac483cf21caf149e74e6a140ee1b091b81b0d8ef29e81d03","cross_cats_sorted":["q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-05-30T13:42:04Z","title_canon_sha256":"8358fd5c9c80d7264b7fe0bb37c006c7509a542ea3f10f244acdf9b36f5528c5"},"schema_version":"1.0","source":{"id":"1605.09230","kind":"arxiv","version":2}},"canonical_sha256":"671e7fcf07b1c61c4236bf5aa9aa3ab4e8671d355a2a2e47dfacf81169ff0db6","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"671e7fcf07b1c61c4236bf5aa9aa3ab4e8671d355a2a2e47dfacf81169ff0db6","first_computed_at":"2026-05-18T00:57:04.426493Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:57:04.426493Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"LJ41nDZw4/05gPf9lapplnO5pJLW/lf86d6xC3/0KPJPnbMyeFvm2lN594n4W4cL3M7KDT8RrY90oKgtXwU/BA==","signature_status":"signed_v1","signed_at":"2026-05-18T00:57:04.427138Z","signed_message":"canonical_sha256_bytes"},"source_id":"1605.09230","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:84a1b64f0429871173b2c90af921fa7476ac8f542a5afe508c7b3fb31f1c6c89","sha256:b37cfe8eaf5536a75e223d34709ac8ae1c71c8eeb5911ad93b09e3edc5220692"],"state_sha256":"ddf4de3aa112ffcb888af1c4ce8451655b77b2f9f2658b7c13637eee940e2764"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"lnIcGISWvjNqQ6C/TyLLirVW0nRIgdj3HTixWXggJumKXI+8pJpTNrrVQyy5KVRDZtQb0msMpG1wx7/8nHJqBg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-23T14:12:53.063726Z","bundle_sha256":"f07a1a70248395fbe19a396069446c9c41ae77e61249686e3e6fd664e87b5f0e"}}