{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:N2J3O2FH2VAM2QSV54BYFRGLMC","short_pith_number":"pith:N2J3O2FH","canonical_record":{"source":{"id":"1809.03135","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.SY","submitted_at":"2018-09-10T04:49:55Z","cross_cats_sorted":["math.OC"],"title_canon_sha256":"4f6e90b8d32cc367d0933ffffc55e436986bcb319ae092bc1a8f5e9ffeccd868","abstract_canon_sha256":"f2dd42d0a176ce21fa1c6dc28e611f8b62eea93661d421634659ca841a8fba1f"},"schema_version":"1.0"},"canonical_sha256":"6e93b768a7d540cd4255ef0382c4cb60ab4074bb222ffa37ccf632f442e3903e","source":{"kind":"arxiv","id":"1809.03135","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1809.03135","created_at":"2026-05-18T00:06:09Z"},{"alias_kind":"arxiv_version","alias_value":"1809.03135v1","created_at":"2026-05-18T00:06:09Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1809.03135","created_at":"2026-05-18T00:06:09Z"},{"alias_kind":"pith_short_12","alias_value":"N2J3O2FH2VAM","created_at":"2026-05-18T12:32:40Z"},{"alias_kind":"pith_short_16","alias_value":"N2J3O2FH2VAM2QSV","created_at":"2026-05-18T12:32:40Z"},{"alias_kind":"pith_short_8","alias_value":"N2J3O2FH","created_at":"2026-05-18T12:32:40Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:N2J3O2FH2VAM2QSV54BYFRGLMC","target":"record","payload":{"canonical_record":{"source":{"id":"1809.03135","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.SY","submitted_at":"2018-09-10T04:49:55Z","cross_cats_sorted":["math.OC"],"title_canon_sha256":"4f6e90b8d32cc367d0933ffffc55e436986bcb319ae092bc1a8f5e9ffeccd868","abstract_canon_sha256":"f2dd42d0a176ce21fa1c6dc28e611f8b62eea93661d421634659ca841a8fba1f"},"schema_version":"1.0"},"canonical_sha256":"6e93b768a7d540cd4255ef0382c4cb60ab4074bb222ffa37ccf632f442e3903e","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:06:09.873678Z","signature_b64":"U79AUYmFLfcu5w5Z6wk0IqfidvXrIpHIOX6T3/oaVVDScLSIGlA6tridaVjPrXYREzEcDB9dIatrIxwEJ/CfBw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"6e93b768a7d540cd4255ef0382c4cb60ab4074bb222ffa37ccf632f442e3903e","last_reissued_at":"2026-05-18T00:06:09.873025Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:06:09.873025Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1809.03135","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:06:09Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"TWq+ZUBRf5kDXwipArbb0KEx+ERRgvIGbz/8hXOsCME5ZRJld/AOkGliSD5pVlM6U38EF9tsJcRC+86GVAPEDg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-25T23:54:53.091988Z"},"content_sha256":"b4427bf9580d97f681db837b21d173305f283582f3c43a8a9b649ae79d7636b1","schema_version":"1.0","event_id":"sha256:b4427bf9580d97f681db837b21d173305f283582f3c43a8a9b649ae79d7636b1"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:N2J3O2FH2VAM2QSV54BYFRGLMC","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"A Linear Approach to Fault Analysis and Intervention in Boolean Systems","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["math.OC"],"primary_cat":"cs.SY","authors_text":"Anuj Deshpande, Ritwik Kumar Layek","submitted_at":"2018-09-10T04:49:55Z","abstract_excerpt":"The mutations of a complex systemic disease like cancer can be modeled as stuck-at faults in the Boolean system paradigm. For a class of multiple faults, the fault identification is exceptionally significant under the incomplete access of all the underlying proteins of the system. A comprehensive linear framework has been developed in this manuscript to identify the class of faults under a set of homeostatic input conditions. An algorithm is developed to design new reporters to improve the observability. The other aspect of this manuscript lies in controlling the manifestation of the mutations"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1809.03135","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:06:09Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"X4JB/2Um7bIsn5PNMVEacmhtl5AvEJVK1GJwRoSI3gIFPRxBtFPD5KrEORIFHDhPRwNhrXU6lB2lfeFWI00hBg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-25T23:54:53.092546Z"},"content_sha256":"30200f612660b4c0c770c1ee82e798bf1bde70e4ec8eb29be38cc1f787667046","schema_version":"1.0","event_id":"sha256:30200f612660b4c0c770c1ee82e798bf1bde70e4ec8eb29be38cc1f787667046"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/N2J3O2FH2VAM2QSV54BYFRGLMC/bundle.json","state_url":"https://pith.science/pith/N2J3O2FH2VAM2QSV54BYFRGLMC/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/N2J3O2FH2VAM2QSV54BYFRGLMC/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-25T23:54:53Z","links":{"resolver":"https://pith.science/pith/N2J3O2FH2VAM2QSV54BYFRGLMC","bundle":"https://pith.science/pith/N2J3O2FH2VAM2QSV54BYFRGLMC/bundle.json","state":"https://pith.science/pith/N2J3O2FH2VAM2QSV54BYFRGLMC/state.json","well_known_bundle":"https://pith.science/.well-known/pith/N2J3O2FH2VAM2QSV54BYFRGLMC/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:N2J3O2FH2VAM2QSV54BYFRGLMC","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"f2dd42d0a176ce21fa1c6dc28e611f8b62eea93661d421634659ca841a8fba1f","cross_cats_sorted":["math.OC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.SY","submitted_at":"2018-09-10T04:49:55Z","title_canon_sha256":"4f6e90b8d32cc367d0933ffffc55e436986bcb319ae092bc1a8f5e9ffeccd868"},"schema_version":"1.0","source":{"id":"1809.03135","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1809.03135","created_at":"2026-05-18T00:06:09Z"},{"alias_kind":"arxiv_version","alias_value":"1809.03135v1","created_at":"2026-05-18T00:06:09Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1809.03135","created_at":"2026-05-18T00:06:09Z"},{"alias_kind":"pith_short_12","alias_value":"N2J3O2FH2VAM","created_at":"2026-05-18T12:32:40Z"},{"alias_kind":"pith_short_16","alias_value":"N2J3O2FH2VAM2QSV","created_at":"2026-05-18T12:32:40Z"},{"alias_kind":"pith_short_8","alias_value":"N2J3O2FH","created_at":"2026-05-18T12:32:40Z"}],"graph_snapshots":[{"event_id":"sha256:30200f612660b4c0c770c1ee82e798bf1bde70e4ec8eb29be38cc1f787667046","target":"graph","created_at":"2026-05-18T00:06:09Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The mutations of a complex systemic disease like cancer can be modeled as stuck-at faults in the Boolean system paradigm. For a class of multiple faults, the fault identification is exceptionally significant under the incomplete access of all the underlying proteins of the system. A comprehensive linear framework has been developed in this manuscript to identify the class of faults under a set of homeostatic input conditions. An algorithm is developed to design new reporters to improve the observability. The other aspect of this manuscript lies in controlling the manifestation of the mutations","authors_text":"Anuj Deshpande, Ritwik Kumar Layek","cross_cats":["math.OC"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.SY","submitted_at":"2018-09-10T04:49:55Z","title":"A Linear Approach to Fault Analysis and Intervention in Boolean Systems"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1809.03135","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:b4427bf9580d97f681db837b21d173305f283582f3c43a8a9b649ae79d7636b1","target":"record","created_at":"2026-05-18T00:06:09Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"f2dd42d0a176ce21fa1c6dc28e611f8b62eea93661d421634659ca841a8fba1f","cross_cats_sorted":["math.OC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.SY","submitted_at":"2018-09-10T04:49:55Z","title_canon_sha256":"4f6e90b8d32cc367d0933ffffc55e436986bcb319ae092bc1a8f5e9ffeccd868"},"schema_version":"1.0","source":{"id":"1809.03135","kind":"arxiv","version":1}},"canonical_sha256":"6e93b768a7d540cd4255ef0382c4cb60ab4074bb222ffa37ccf632f442e3903e","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"6e93b768a7d540cd4255ef0382c4cb60ab4074bb222ffa37ccf632f442e3903e","first_computed_at":"2026-05-18T00:06:09.873025Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:06:09.873025Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"U79AUYmFLfcu5w5Z6wk0IqfidvXrIpHIOX6T3/oaVVDScLSIGlA6tridaVjPrXYREzEcDB9dIatrIxwEJ/CfBw==","signature_status":"signed_v1","signed_at":"2026-05-18T00:06:09.873678Z","signed_message":"canonical_sha256_bytes"},"source_id":"1809.03135","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:b4427bf9580d97f681db837b21d173305f283582f3c43a8a9b649ae79d7636b1","sha256:30200f612660b4c0c770c1ee82e798bf1bde70e4ec8eb29be38cc1f787667046"],"state_sha256":"36186ca7ff2b59fab5f45cb992113157f73b46af05aa6dc2e63701e4ac5718ab"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"1QOadfg4+z7EqtO3lhZRuhhcji+Wv5G5Quvbd6mBejo0KvzA4fjtg+G5UvMJp5zFwOGw4F8RQPEsqQFL5n4WCQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-25T23:54:53.095165Z","bundle_sha256":"978c0247bba7a0ed318271266b5f3821ac555b96de78314c7765992b90d3ebd5"}}