{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2026:N2PILTKKQOJYJVLRVBFPF3HUHW","short_pith_number":"pith:N2PILTKK","canonical_record":{"source":{"id":"2606.23172","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"eess.IV","submitted_at":"2026-06-22T11:11:26Z","cross_cats_sorted":[],"title_canon_sha256":"2056824a460135c3b4b4ed855f7cd03a9cb2db0baace7000e25b7c9bd3624b8d","abstract_canon_sha256":"e1e646b6d67c8b567a11eec70b067844781fc3ce5942001a7da7c005d1252a1d"},"schema_version":"1.0"},"canonical_sha256":"6e9e85cd4a839384d571a84af2ecf43d82a0589a1840ecb635a0c7d29783a44f","source":{"kind":"arxiv","id":"2606.23172","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2606.23172","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"arxiv_version","alias_value":"2606.23172v1","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2606.23172","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"pith_short_12","alias_value":"N2PILTKKQOJY","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"pith_short_16","alias_value":"N2PILTKKQOJYJVLR","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"pith_short_8","alias_value":"N2PILTKK","created_at":"2026-06-23T03:14:12Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2026:N2PILTKKQOJYJVLRVBFPF3HUHW","target":"record","payload":{"canonical_record":{"source":{"id":"2606.23172","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"eess.IV","submitted_at":"2026-06-22T11:11:26Z","cross_cats_sorted":[],"title_canon_sha256":"2056824a460135c3b4b4ed855f7cd03a9cb2db0baace7000e25b7c9bd3624b8d","abstract_canon_sha256":"e1e646b6d67c8b567a11eec70b067844781fc3ce5942001a7da7c005d1252a1d"},"schema_version":"1.0"},"canonical_sha256":"6e9e85cd4a839384d571a84af2ecf43d82a0589a1840ecb635a0c7d29783a44f","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-06-23T03:14:12.045342Z","signature_b64":"+6SDWgA/KKuaoJsLuiXvLpoBO1CfXVzC//Va87yHfv2Fz/8TP8kbsS694DZNwkZXXf9e5dhSuhrFcLHqrQASBw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"6e9e85cd4a839384d571a84af2ecf43d82a0589a1840ecb635a0c7d29783a44f","last_reissued_at":"2026-06-23T03:14:12.044991Z","signature_status":"signed_v1","first_computed_at":"2026-06-23T03:14:12.044991Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2606.23172","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-06-23T03:14:12Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"yhl0fOkREKO4b7glYKortnCnL4MPiibZrEBukFG1PJMAWYpWmMFDdidF+HLq1SAlc2x8xJMmvhl7SLo8785KCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-29T12:51:16.170125Z"},"content_sha256":"c780e78bf517148c47f135cbc5dd3b330d9d87e0fcaf89e62e26d5df7b6d505b","schema_version":"1.0","event_id":"sha256:c780e78bf517148c47f135cbc5dd3b330d9d87e0fcaf89e62e26d5df7b6d505b"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2026:N2PILTKKQOJYJVLRVBFPF3HUHW","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"A Benchmark of (MRI-) Foundation Models to Predict IDH Mutational Status in Glioma","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"eess.IV","authors_text":"Efthymios Georgiou, Ekin Ermis, Elise Robinson, Nathan Hollet, Sarah Br\\\"uningk, Uri Nahum","submitted_at":"2026-06-22T11:11:26Z","abstract_excerpt":"Non-invasive prediction of glioma molecular status from routine magnetic resonance imaging (MRI) has shown promising performance, but model generalization remains challenging given small-scale matched imaging-genomic datasets. Foundation models may address this bottleneck, but a comprehensive benchmark is needed to establish the impact of diverse architectures, pre-training domains, and objectives. Given the use case of isocitrate dehydrogenase (IDH) mutation prediction from FLAIR and post-contrast T1 MRIs, we compared four image-based foundation models, BrainIAC, MRI-CORE, BiomedCLIP, and Bra"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2606.23172","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2606.23172/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-06-23T03:14:12Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"VG6ViFa5YkH6kPWVf1sNHZeNb1r2O3doSS3e3ICqb+Pwx6gwqgGQCZaxjVkCEWRfXVTzfzC4p4sRIVI9Kh9GDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-29T12:51:16.170517Z"},"content_sha256":"3853a3965ac7fd3391758a2145557a947f9b81f0479da91513fef7915a1cb656","schema_version":"1.0","event_id":"sha256:3853a3965ac7fd3391758a2145557a947f9b81f0479da91513fef7915a1cb656"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/N2PILTKKQOJYJVLRVBFPF3HUHW/bundle.json","state_url":"https://pith.science/pith/N2PILTKKQOJYJVLRVBFPF3HUHW/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/N2PILTKKQOJYJVLRVBFPF3HUHW/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-29T12:51:16Z","links":{"resolver":"https://pith.science/pith/N2PILTKKQOJYJVLRVBFPF3HUHW","bundle":"https://pith.science/pith/N2PILTKKQOJYJVLRVBFPF3HUHW/bundle.json","state":"https://pith.science/pith/N2PILTKKQOJYJVLRVBFPF3HUHW/state.json","well_known_bundle":"https://pith.science/.well-known/pith/N2PILTKKQOJYJVLRVBFPF3HUHW/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2026:N2PILTKKQOJYJVLRVBFPF3HUHW","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"e1e646b6d67c8b567a11eec70b067844781fc3ce5942001a7da7c005d1252a1d","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"eess.IV","submitted_at":"2026-06-22T11:11:26Z","title_canon_sha256":"2056824a460135c3b4b4ed855f7cd03a9cb2db0baace7000e25b7c9bd3624b8d"},"schema_version":"1.0","source":{"id":"2606.23172","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2606.23172","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"arxiv_version","alias_value":"2606.23172v1","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2606.23172","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"pith_short_12","alias_value":"N2PILTKKQOJY","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"pith_short_16","alias_value":"N2PILTKKQOJYJVLR","created_at":"2026-06-23T03:14:12Z"},{"alias_kind":"pith_short_8","alias_value":"N2PILTKK","created_at":"2026-06-23T03:14:12Z"}],"graph_snapshots":[{"event_id":"sha256:3853a3965ac7fd3391758a2145557a947f9b81f0479da91513fef7915a1cb656","target":"graph","created_at":"2026-06-23T03:14:12Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2606.23172/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Non-invasive prediction of glioma molecular status from routine magnetic resonance imaging (MRI) has shown promising performance, but model generalization remains challenging given small-scale matched imaging-genomic datasets. Foundation models may address this bottleneck, but a comprehensive benchmark is needed to establish the impact of diverse architectures, pre-training domains, and objectives. Given the use case of isocitrate dehydrogenase (IDH) mutation prediction from FLAIR and post-contrast T1 MRIs, we compared four image-based foundation models, BrainIAC, MRI-CORE, BiomedCLIP, and Bra","authors_text":"Efthymios Georgiou, Ekin Ermis, Elise Robinson, Nathan Hollet, Sarah Br\\\"uningk, Uri Nahum","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"eess.IV","submitted_at":"2026-06-22T11:11:26Z","title":"A Benchmark of (MRI-) Foundation Models to Predict IDH Mutational Status in Glioma"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2606.23172","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:c780e78bf517148c47f135cbc5dd3b330d9d87e0fcaf89e62e26d5df7b6d505b","target":"record","created_at":"2026-06-23T03:14:12Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"e1e646b6d67c8b567a11eec70b067844781fc3ce5942001a7da7c005d1252a1d","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"eess.IV","submitted_at":"2026-06-22T11:11:26Z","title_canon_sha256":"2056824a460135c3b4b4ed855f7cd03a9cb2db0baace7000e25b7c9bd3624b8d"},"schema_version":"1.0","source":{"id":"2606.23172","kind":"arxiv","version":1}},"canonical_sha256":"6e9e85cd4a839384d571a84af2ecf43d82a0589a1840ecb635a0c7d29783a44f","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"6e9e85cd4a839384d571a84af2ecf43d82a0589a1840ecb635a0c7d29783a44f","first_computed_at":"2026-06-23T03:14:12.044991Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-06-23T03:14:12.044991Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"+6SDWgA/KKuaoJsLuiXvLpoBO1CfXVzC//Va87yHfv2Fz/8TP8kbsS694DZNwkZXXf9e5dhSuhrFcLHqrQASBw==","signature_status":"signed_v1","signed_at":"2026-06-23T03:14:12.045342Z","signed_message":"canonical_sha256_bytes"},"source_id":"2606.23172","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:c780e78bf517148c47f135cbc5dd3b330d9d87e0fcaf89e62e26d5df7b6d505b","sha256:3853a3965ac7fd3391758a2145557a947f9b81f0479da91513fef7915a1cb656"],"state_sha256":"115373ea8fb5ce7bed2b71939f1219cb09abd2ee178e92130805e89e858e490f"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"nOEHsCzsPnjNw14kX2dFEo42vBXr54YK/VFI2CZ3jJIy4FDN+do3RV/cS5d0YRvFX3naDZNE4o8STzpKUkGyCA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-29T12:51:16.172383Z","bundle_sha256":"69627a54344af1b150fc310c393fcde916be95c0ac69a466e79d35d9d77c832f"}}