{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2011:OJCY7WFF52LS52JGLTM3QGGQMV","short_pith_number":"pith:OJCY7WFF","schema_version":"1.0","canonical_sha256":"72458fd8a5ee972ee9265cd9b818d0657dd4679286b9350e9adefe2636d911d5","source":{"kind":"arxiv","id":"1110.4724","version":2},"attestation_state":"computed","paper":{"title":"Flexible and robust patterning by centralized gene networks","license":"http://creativecommons.org/licenses/publicdomain/","headline":"","cross_cats":["math.AP","nlin.PS"],"primary_cat":"q-bio.MN","authors_text":"Ovidiu Radulescu, Sergei Vakulenko","submitted_at":"2011-10-21T08:00:27Z","abstract_excerpt":"We consider networks with two types of nodes. The v-nodes, called centers, are hyperconnected and interact one to another via many u-nodes, called satellites. This centralized architecture, widespread in gene networks, realize a bow-tie scheme and possesses interesting properties. Namely, this organization creates feedback loops that are capable to generate any prescribed patterning dynamics, chaotic or periodic, and create a number of equilibrium states. We show that activation or silencing of a node can sharply switch the network attractor, even if the activated or silenced node is weakly co"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1110.4724","kind":"arxiv","version":2},"metadata":{"license":"http://creativecommons.org/licenses/publicdomain/","primary_cat":"q-bio.MN","submitted_at":"2011-10-21T08:00:27Z","cross_cats_sorted":["math.AP","nlin.PS"],"title_canon_sha256":"f5f2829f6b59cab1a217b71302e7432e92fe4a81811381f898aee1fc8f00aaa1","abstract_canon_sha256":"46d2cc7b03164c8470ac7200bcc4b7490452d7028b541dbe53c2df01b59f7706"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T04:01:11.362689Z","signature_b64":"nWSO5xCexeazHnI+/LIDA7j3cc6Rl2FSynCbE0UURcZXFXV2gqaqhIcC9kVU1zAhT8U0tGKW9hN3mOLh+XHQDw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"72458fd8a5ee972ee9265cd9b818d0657dd4679286b9350e9adefe2636d911d5","last_reissued_at":"2026-05-18T04:01:11.362083Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T04:01:11.362083Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Flexible and robust patterning by centralized gene networks","license":"http://creativecommons.org/licenses/publicdomain/","headline":"","cross_cats":["math.AP","nlin.PS"],"primary_cat":"q-bio.MN","authors_text":"Ovidiu Radulescu, Sergei Vakulenko","submitted_at":"2011-10-21T08:00:27Z","abstract_excerpt":"We consider networks with two types of nodes. The v-nodes, called centers, are hyperconnected and interact one to another via many u-nodes, called satellites. This centralized architecture, widespread in gene networks, realize a bow-tie scheme and possesses interesting properties. Namely, this organization creates feedback loops that are capable to generate any prescribed patterning dynamics, chaotic or periodic, and create a number of equilibrium states. We show that activation or silencing of a node can sharply switch the network attractor, even if the activated or silenced node is weakly co"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1110.4724","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1110.4724","created_at":"2026-05-18T04:01:11.362171+00:00"},{"alias_kind":"arxiv_version","alias_value":"1110.4724v2","created_at":"2026-05-18T04:01:11.362171+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1110.4724","created_at":"2026-05-18T04:01:11.362171+00:00"},{"alias_kind":"pith_short_12","alias_value":"OJCY7WFF52LS","created_at":"2026-05-18T12:26:37.096874+00:00"},{"alias_kind":"pith_short_16","alias_value":"OJCY7WFF52LS52JG","created_at":"2026-05-18T12:26:37.096874+00:00"},{"alias_kind":"pith_short_8","alias_value":"OJCY7WFF","created_at":"2026-05-18T12:26:37.096874+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/OJCY7WFF52LS52JGLTM3QGGQMV","json":"https://pith.science/pith/OJCY7WFF52LS52JGLTM3QGGQMV.json","graph_json":"https://pith.science/api/pith-number/OJCY7WFF52LS52JGLTM3QGGQMV/graph.json","events_json":"https://pith.science/api/pith-number/OJCY7WFF52LS52JGLTM3QGGQMV/events.json","paper":"https://pith.science/paper/OJCY7WFF"},"agent_actions":{"view_html":"https://pith.science/pith/OJCY7WFF52LS52JGLTM3QGGQMV","download_json":"https://pith.science/pith/OJCY7WFF52LS52JGLTM3QGGQMV.json","view_paper":"https://pith.science/paper/OJCY7WFF","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1110.4724&json=true","fetch_graph":"https://pith.science/api/pith-number/OJCY7WFF52LS52JGLTM3QGGQMV/graph.json","fetch_events":"https://pith.science/api/pith-number/OJCY7WFF52LS52JGLTM3QGGQMV/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/OJCY7WFF52LS52JGLTM3QGGQMV/action/timestamp_anchor","attest_storage":"https://pith.science/pith/OJCY7WFF52LS52JGLTM3QGGQMV/action/storage_attestation","attest_author":"https://pith.science/pith/OJCY7WFF52LS52JGLTM3QGGQMV/action/author_attestation","sign_citation":"https://pith.science/pith/OJCY7WFF52LS52JGLTM3QGGQMV/action/citation_signature","submit_replication":"https://pith.science/pith/OJCY7WFF52LS52JGLTM3QGGQMV/action/replication_record"}},"created_at":"2026-05-18T04:01:11.362171+00:00","updated_at":"2026-05-18T04:01:11.362171+00:00"}