{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2022:PZP4FYCPKL6X4YQFJTY6ND72TV","short_pith_number":"pith:PZP4FYCP","canonical_record":{"source":{"id":"2208.05939","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-08-11T17:26:09Z","cross_cats_sorted":["cs.CV","cs.LG"],"title_canon_sha256":"0eea4f4667a12e0519f3cdeb0f6282b876b60a50ad70e051066ce287a5268734","abstract_canon_sha256":"cf89bc62f37630edff41a57ace3cebc8da343b327e131414e2ee4963858d6092"},"schema_version":"1.0"},"canonical_sha256":"7e5fc2e04f52fd7e62054cf1e68ffa9d78190c53990b085ff05d4ba59cd71e98","source":{"kind":"arxiv","id":"2208.05939","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2208.05939","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"arxiv_version","alias_value":"2208.05939v1","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2208.05939","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"pith_short_12","alias_value":"PZP4FYCPKL6X","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"pith_short_16","alias_value":"PZP4FYCPKL6X4YQF","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"pith_short_8","alias_value":"PZP4FYCP","created_at":"2026-07-05T04:47:53Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2022:PZP4FYCPKL6X4YQFJTY6ND72TV","target":"record","payload":{"canonical_record":{"source":{"id":"2208.05939","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-08-11T17:26:09Z","cross_cats_sorted":["cs.CV","cs.LG"],"title_canon_sha256":"0eea4f4667a12e0519f3cdeb0f6282b876b60a50ad70e051066ce287a5268734","abstract_canon_sha256":"cf89bc62f37630edff41a57ace3cebc8da343b327e131414e2ee4963858d6092"},"schema_version":"1.0"},"canonical_sha256":"7e5fc2e04f52fd7e62054cf1e68ffa9d78190c53990b085ff05d4ba59cd71e98","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T04:47:53.786347Z","signature_b64":"Wz5zCEFbttzUc7iZ61x7EE61gIXDlSO9DrLMuWRR3JkM/P+vVayZ6tIEGIIU64JSsZkMRCY5OVFiRXr+F3vtAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"7e5fc2e04f52fd7e62054cf1e68ffa9d78190c53990b085ff05d4ba59cd71e98","last_reissued_at":"2026-07-05T04:47:53.785861Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T04:47:53.785861Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2208.05939","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:47:53Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"qXkkkv3A+CS2gXkXl+lvzc7g0/xOXdOEGwRwYwS3vh7BBCe7rBl7zJoL1IA2mtvl1213N9fMxVVDEdHY6DmRAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-23T18:35:53.195729Z"},"content_sha256":"5e4119990aeaaabed518b9855a9a0bc5debd83047fd7b3e3a0c04b8efd4e80be","schema_version":"1.0","event_id":"sha256:5e4119990aeaaabed518b9855a9a0bc5debd83047fd7b3e3a0c04b8efd4e80be"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2022:PZP4FYCPKL6X4YQFJTY6ND72TV","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Heatmap Regression for Lesion Detection using Pointwise Annotations","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.CV","cs.LG"],"primary_cat":"eess.IV","authors_text":"Chelsea Myers-Colet, Douglas L. Arnold, Julien Schroeter, Tal Arbel","submitted_at":"2022-08-11T17:26:09Z","abstract_excerpt":"In many clinical contexts, detecting all lesions is imperative for evaluating disease activity. Standard approaches pose lesion detection as a segmentation problem despite the time-consuming nature of acquiring segmentation labels. In this paper, we present a lesion detection method which relies only on point labels. Our model, which is trained via heatmap regression, can detect a variable number of lesions in a probabilistic manner. In fact, our proposed post-processing method offers a reliable way of directly estimating the lesion existence uncertainty. Experimental results on Gad lesion det"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2208.05939","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2208.05939/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:47:53Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"VXZmbYYkEDomkFXdvFwOpcqr4LuDESFzbSUe6/TLXjJZ+ST9OoSW32XxxGRgvWpmVVrUKrvTKg0zRdOQkUq0Dw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-23T18:35:53.196270Z"},"content_sha256":"7d8283091381984eea292665ce376103569910ae561cf1500fb58ffa95565e28","schema_version":"1.0","event_id":"sha256:7d8283091381984eea292665ce376103569910ae561cf1500fb58ffa95565e28"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/PZP4FYCPKL6X4YQFJTY6ND72TV/bundle.json","state_url":"https://pith.science/pith/PZP4FYCPKL6X4YQFJTY6ND72TV/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/PZP4FYCPKL6X4YQFJTY6ND72TV/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-23T18:35:53Z","links":{"resolver":"https://pith.science/pith/PZP4FYCPKL6X4YQFJTY6ND72TV","bundle":"https://pith.science/pith/PZP4FYCPKL6X4YQFJTY6ND72TV/bundle.json","state":"https://pith.science/pith/PZP4FYCPKL6X4YQFJTY6ND72TV/state.json","well_known_bundle":"https://pith.science/.well-known/pith/PZP4FYCPKL6X4YQFJTY6ND72TV/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2022:PZP4FYCPKL6X4YQFJTY6ND72TV","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"cf89bc62f37630edff41a57ace3cebc8da343b327e131414e2ee4963858d6092","cross_cats_sorted":["cs.CV","cs.LG"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-08-11T17:26:09Z","title_canon_sha256":"0eea4f4667a12e0519f3cdeb0f6282b876b60a50ad70e051066ce287a5268734"},"schema_version":"1.0","source":{"id":"2208.05939","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2208.05939","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"arxiv_version","alias_value":"2208.05939v1","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2208.05939","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"pith_short_12","alias_value":"PZP4FYCPKL6X","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"pith_short_16","alias_value":"PZP4FYCPKL6X4YQF","created_at":"2026-07-05T04:47:53Z"},{"alias_kind":"pith_short_8","alias_value":"PZP4FYCP","created_at":"2026-07-05T04:47:53Z"}],"graph_snapshots":[{"event_id":"sha256:7d8283091381984eea292665ce376103569910ae561cf1500fb58ffa95565e28","target":"graph","created_at":"2026-07-05T04:47:53Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2208.05939/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"In many clinical contexts, detecting all lesions is imperative for evaluating disease activity. Standard approaches pose lesion detection as a segmentation problem despite the time-consuming nature of acquiring segmentation labels. In this paper, we present a lesion detection method which relies only on point labels. Our model, which is trained via heatmap regression, can detect a variable number of lesions in a probabilistic manner. In fact, our proposed post-processing method offers a reliable way of directly estimating the lesion existence uncertainty. Experimental results on Gad lesion det","authors_text":"Chelsea Myers-Colet, Douglas L. Arnold, Julien Schroeter, Tal Arbel","cross_cats":["cs.CV","cs.LG"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-08-11T17:26:09Z","title":"Heatmap Regression for Lesion Detection using Pointwise Annotations"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2208.05939","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:5e4119990aeaaabed518b9855a9a0bc5debd83047fd7b3e3a0c04b8efd4e80be","target":"record","created_at":"2026-07-05T04:47:53Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"cf89bc62f37630edff41a57ace3cebc8da343b327e131414e2ee4963858d6092","cross_cats_sorted":["cs.CV","cs.LG"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-08-11T17:26:09Z","title_canon_sha256":"0eea4f4667a12e0519f3cdeb0f6282b876b60a50ad70e051066ce287a5268734"},"schema_version":"1.0","source":{"id":"2208.05939","kind":"arxiv","version":1}},"canonical_sha256":"7e5fc2e04f52fd7e62054cf1e68ffa9d78190c53990b085ff05d4ba59cd71e98","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"7e5fc2e04f52fd7e62054cf1e68ffa9d78190c53990b085ff05d4ba59cd71e98","first_computed_at":"2026-07-05T04:47:53.785861Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T04:47:53.785861Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"Wz5zCEFbttzUc7iZ61x7EE61gIXDlSO9DrLMuWRR3JkM/P+vVayZ6tIEGIIU64JSsZkMRCY5OVFiRXr+F3vtAg==","signature_status":"signed_v1","signed_at":"2026-07-05T04:47:53.786347Z","signed_message":"canonical_sha256_bytes"},"source_id":"2208.05939","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:5e4119990aeaaabed518b9855a9a0bc5debd83047fd7b3e3a0c04b8efd4e80be","sha256:7d8283091381984eea292665ce376103569910ae561cf1500fb58ffa95565e28"],"state_sha256":"5a40db3c287a9cd8565eeef93cdcc18a04a5135cad4d0a8ab62ca444b4d49855"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"UEqJhEv4dVejqSd/0x0FeiQNvy3bDOqNwPDoFZlMF/ikKtsvR4kX0EkYIVH99xtB6uEt6TIkxkqgw76ZEWi0CQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-23T18:35:53.200110Z","bundle_sha256":"497fa126e01c4e6e03389bc0ef724c5bb1d1addb228e72ec14880a9cbd7a00ac"}}