{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2013:RGHC6FS5HPU277U236UAXZ7OFZ","short_pith_number":"pith:RGHC6FS5","canonical_record":{"source":{"id":"1304.3786","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"math.PR","submitted_at":"2013-04-13T07:34:12Z","cross_cats_sorted":["q-bio.SC"],"title_canon_sha256":"1155e3b6498550a001080d347541674e92d1df1040be5816fca3fe207806e073","abstract_canon_sha256":"f681ecc157360fa73c18a9e0f5b63c83e455982b18fc7309a886d628022e943b"},"schema_version":"1.0"},"canonical_sha256":"898e2f165d3be9affe9adfa80be7ee2e6ff66c63d035029250d79fd2b61bd4b2","source":{"kind":"arxiv","id":"1304.3786","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1304.3786","created_at":"2026-05-18T03:28:04Z"},{"alias_kind":"arxiv_version","alias_value":"1304.3786v1","created_at":"2026-05-18T03:28:04Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1304.3786","created_at":"2026-05-18T03:28:04Z"},{"alias_kind":"pith_short_12","alias_value":"RGHC6FS5HPU2","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_16","alias_value":"RGHC6FS5HPU277U2","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_8","alias_value":"RGHC6FS5","created_at":"2026-05-18T12:27:57Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2013:RGHC6FS5HPU277U236UAXZ7OFZ","target":"record","payload":{"canonical_record":{"source":{"id":"1304.3786","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"math.PR","submitted_at":"2013-04-13T07:34:12Z","cross_cats_sorted":["q-bio.SC"],"title_canon_sha256":"1155e3b6498550a001080d347541674e92d1df1040be5816fca3fe207806e073","abstract_canon_sha256":"f681ecc157360fa73c18a9e0f5b63c83e455982b18fc7309a886d628022e943b"},"schema_version":"1.0"},"canonical_sha256":"898e2f165d3be9affe9adfa80be7ee2e6ff66c63d035029250d79fd2b61bd4b2","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T03:28:04.358853Z","signature_b64":"Mo+cniqGIGjyqzSufxjHTQRARyLqWBuMiux/6ehzq9OOVEXgY3NZJrAL5CmZKnZ74+nYwb1M6iwwfNmm7R2nBw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"898e2f165d3be9affe9adfa80be7ee2e6ff66c63d035029250d79fd2b61bd4b2","last_reissued_at":"2026-05-18T03:28:04.358119Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T03:28:04.358119Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1304.3786","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:28:04Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"88x9Q0qA46RXrTphVKsk3nuGGjgSQ2r6vhYuJom2oH0A3lj9iysXsUFNKFBXV8VsOEND2c26d3LSEyZaKUMYCQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-24T04:44:48.758522Z"},"content_sha256":"b4be3c3678c3a515b6aa7201ef16738cf71e7d8246d51b49f662e01ffe3eba47","schema_version":"1.0","event_id":"sha256:b4be3c3678c3a515b6aa7201ef16738cf71e7d8246d51b49f662e01ffe3eba47"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2013:RGHC6FS5HPU277U236UAXZ7OFZ","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Stochastic Modelling of T-Cell-Activation","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.SC"],"primary_cat":"math.PR","authors_text":"Anton Bovier, Hannah Mayer","submitted_at":"2013-04-13T07:34:12Z","abstract_excerpt":"We investigate a special part of the human immune system, namely the activation of T-Cells, using stochastic tools, especially sharp large deviation results. T-Cells have to distinguish reliably between foreign and self peptides which are both presented to them by antigen presenting cells. Our work is based on a model studied by Zint, Baake, and den Hollander, and originally proposed by van den Berg, Rand, and Burroughs. We are able to dispense with some restrictive distribution assumptions that were used previously, i.e. we establish a higher robustness of the model. A central issue is the an"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1304.3786","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:28:04Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"RUGGF+9t1acqtld0dfdfzfBgY68vsS8YGPzZFGxa3zJr2oeHKriVb9f3nF6tr0Crv+6XI70Jepx+IVeMl5hDAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-24T04:44:48.758871Z"},"content_sha256":"59743e7005fa88e624f68b27752c6db37910fe5feeca3ace1e01613136ca401a","schema_version":"1.0","event_id":"sha256:59743e7005fa88e624f68b27752c6db37910fe5feeca3ace1e01613136ca401a"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/RGHC6FS5HPU277U236UAXZ7OFZ/bundle.json","state_url":"https://pith.science/pith/RGHC6FS5HPU277U236UAXZ7OFZ/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/RGHC6FS5HPU277U236UAXZ7OFZ/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-24T04:44:48Z","links":{"resolver":"https://pith.science/pith/RGHC6FS5HPU277U236UAXZ7OFZ","bundle":"https://pith.science/pith/RGHC6FS5HPU277U236UAXZ7OFZ/bundle.json","state":"https://pith.science/pith/RGHC6FS5HPU277U236UAXZ7OFZ/state.json","well_known_bundle":"https://pith.science/.well-known/pith/RGHC6FS5HPU277U236UAXZ7OFZ/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2013:RGHC6FS5HPU277U236UAXZ7OFZ","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"f681ecc157360fa73c18a9e0f5b63c83e455982b18fc7309a886d628022e943b","cross_cats_sorted":["q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"math.PR","submitted_at":"2013-04-13T07:34:12Z","title_canon_sha256":"1155e3b6498550a001080d347541674e92d1df1040be5816fca3fe207806e073"},"schema_version":"1.0","source":{"id":"1304.3786","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1304.3786","created_at":"2026-05-18T03:28:04Z"},{"alias_kind":"arxiv_version","alias_value":"1304.3786v1","created_at":"2026-05-18T03:28:04Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1304.3786","created_at":"2026-05-18T03:28:04Z"},{"alias_kind":"pith_short_12","alias_value":"RGHC6FS5HPU2","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_16","alias_value":"RGHC6FS5HPU277U2","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_8","alias_value":"RGHC6FS5","created_at":"2026-05-18T12:27:57Z"}],"graph_snapshots":[{"event_id":"sha256:59743e7005fa88e624f68b27752c6db37910fe5feeca3ace1e01613136ca401a","target":"graph","created_at":"2026-05-18T03:28:04Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"We investigate a special part of the human immune system, namely the activation of T-Cells, using stochastic tools, especially sharp large deviation results. T-Cells have to distinguish reliably between foreign and self peptides which are both presented to them by antigen presenting cells. Our work is based on a model studied by Zint, Baake, and den Hollander, and originally proposed by van den Berg, Rand, and Burroughs. We are able to dispense with some restrictive distribution assumptions that were used previously, i.e. we establish a higher robustness of the model. A central issue is the an","authors_text":"Anton Bovier, Hannah Mayer","cross_cats":["q-bio.SC"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"math.PR","submitted_at":"2013-04-13T07:34:12Z","title":"Stochastic Modelling of T-Cell-Activation"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1304.3786","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:b4be3c3678c3a515b6aa7201ef16738cf71e7d8246d51b49f662e01ffe3eba47","target":"record","created_at":"2026-05-18T03:28:04Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"f681ecc157360fa73c18a9e0f5b63c83e455982b18fc7309a886d628022e943b","cross_cats_sorted":["q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"math.PR","submitted_at":"2013-04-13T07:34:12Z","title_canon_sha256":"1155e3b6498550a001080d347541674e92d1df1040be5816fca3fe207806e073"},"schema_version":"1.0","source":{"id":"1304.3786","kind":"arxiv","version":1}},"canonical_sha256":"898e2f165d3be9affe9adfa80be7ee2e6ff66c63d035029250d79fd2b61bd4b2","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"898e2f165d3be9affe9adfa80be7ee2e6ff66c63d035029250d79fd2b61bd4b2","first_computed_at":"2026-05-18T03:28:04.358119Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T03:28:04.358119Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"Mo+cniqGIGjyqzSufxjHTQRARyLqWBuMiux/6ehzq9OOVEXgY3NZJrAL5CmZKnZ74+nYwb1M6iwwfNmm7R2nBw==","signature_status":"signed_v1","signed_at":"2026-05-18T03:28:04.358853Z","signed_message":"canonical_sha256_bytes"},"source_id":"1304.3786","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:b4be3c3678c3a515b6aa7201ef16738cf71e7d8246d51b49f662e01ffe3eba47","sha256:59743e7005fa88e624f68b27752c6db37910fe5feeca3ace1e01613136ca401a"],"state_sha256":"baf1950cd0075a06fe5e0e2bbc48767ebee721a8fc54b07da70c3c76c077d5f6"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"4xHt0nH6SSgdwsuFnLgOGbIasEoDK3h01pi3z9P2mvn2uYUffUbyf8F/28D48nNrQGzK+FNTBhq9uiA6UDT/AA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-24T04:44:48.760858Z","bundle_sha256":"99417b3dea1f7d12adbb1c09e8c6e9143476218f8eb1e9e54606432b7c048d80"}}