{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2022:SM3VX2MV65FT6YJ6Y6BVGZXEMK","short_pith_number":"pith:SM3VX2MV","canonical_record":{"source":{"id":"2203.10852","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CV","submitted_at":"2022-03-21T10:20:04Z","cross_cats_sorted":["cs.AI"],"title_canon_sha256":"18886b4266bfefed98b8f95a4c2d2f782940a4d62c84665eac17d8dd133c3bcb","abstract_canon_sha256":"53cd8444bfbb5c35deffcc5af5e8fe57ef6926bdc2e5d1d74aa1dd4f7e1531c7"},"schema_version":"1.0"},"canonical_sha256":"93375be995f74b3f613ec7835366e4628da4963c0fd28966fa9aac4f6300ae35","source":{"kind":"arxiv","id":"2203.10852","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2203.10852","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"arxiv_version","alias_value":"2203.10852v1","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2203.10852","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"pith_short_12","alias_value":"SM3VX2MV65FT","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"pith_short_16","alias_value":"SM3VX2MV65FT6YJ6","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"pith_short_8","alias_value":"SM3VX2MV","created_at":"2026-07-05T04:06:57Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2022:SM3VX2MV65FT6YJ6Y6BVGZXEMK","target":"record","payload":{"canonical_record":{"source":{"id":"2203.10852","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CV","submitted_at":"2022-03-21T10:20:04Z","cross_cats_sorted":["cs.AI"],"title_canon_sha256":"18886b4266bfefed98b8f95a4c2d2f782940a4d62c84665eac17d8dd133c3bcb","abstract_canon_sha256":"53cd8444bfbb5c35deffcc5af5e8fe57ef6926bdc2e5d1d74aa1dd4f7e1531c7"},"schema_version":"1.0"},"canonical_sha256":"93375be995f74b3f613ec7835366e4628da4963c0fd28966fa9aac4f6300ae35","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T04:06:57.985497Z","signature_b64":"Jkjm/n2gXFpU080EzqbMZQxz71/LCsYFyb4hz9DPNcCU6ZHy4Zsj0rYe/V5q5TrRppexcK1Z5hXFvEViobgeBg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"93375be995f74b3f613ec7835366e4628da4963c0fd28966fa9aac4f6300ae35","last_reissued_at":"2026-07-05T04:06:57.985063Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T04:06:57.985063Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2203.10852","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:06:57Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"BllA8jektBErKBCfq+31HQHnug15Vb6MZLrn4D8IIbpR+f+eehFDcrJAC7SNX6SvUhhep+7PsJ4wA6cHVu0dCQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-14T01:29:49.522921Z"},"content_sha256":"faf293151dd1b86cfbbd4d8e154a502e37da2bbc3ce136b499c71aee4cc71ccf","schema_version":"1.0","event_id":"sha256:faf293151dd1b86cfbbd4d8e154a502e37da2bbc3ce136b499c71aee4cc71ccf"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2022:SM3VX2MV65FT6YJ6Y6BVGZXEMK","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Multi-modal learning for predicting the genotype of glioma","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","headline":"","cross_cats":["cs.AI"],"primary_cat":"cs.CV","authors_text":"Carola-Bibiane Sch\\\"onlieb, Chao Li, Lei Zhu, Lipei Zhang, Stephen J. Price, Xi Chen, Yiran Wei","submitted_at":"2022-03-21T10:20:04Z","abstract_excerpt":"The isocitrate dehydrogenase (IDH) gene mutation is an essential biomarker for the diagnosis and prognosis of glioma. It is promising to better predict glioma genotype by integrating focal tumor image and geometric features with brain network features derived from MRI. Convolutions neural networks show reasonable performance in predicting IDH mutation, which, however, cannot learn from non-Euclidean data, e.g., geometric and network data. In this study, we propose a multi-modal learning framework using three separate encoders to extract features of focal tumor image, tumor geometrics and globa"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2203.10852","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2203.10852/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:06:57Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"5AjEZosvbUTMp4+wrTqiI6G6rhDf45HARMpyTW6PD4dDjT1JaTtlOidzgGxhZumovRyFIebbQvhaTNY6GCcIBQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-14T01:29:49.523243Z"},"content_sha256":"596d9fbf4e4cdae1f62fb1e49cce909d4cf7148cc46fee4518d5ac5b2439361a","schema_version":"1.0","event_id":"sha256:596d9fbf4e4cdae1f62fb1e49cce909d4cf7148cc46fee4518d5ac5b2439361a"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/SM3VX2MV65FT6YJ6Y6BVGZXEMK/bundle.json","state_url":"https://pith.science/pith/SM3VX2MV65FT6YJ6Y6BVGZXEMK/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/SM3VX2MV65FT6YJ6Y6BVGZXEMK/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-14T01:29:49Z","links":{"resolver":"https://pith.science/pith/SM3VX2MV65FT6YJ6Y6BVGZXEMK","bundle":"https://pith.science/pith/SM3VX2MV65FT6YJ6Y6BVGZXEMK/bundle.json","state":"https://pith.science/pith/SM3VX2MV65FT6YJ6Y6BVGZXEMK/state.json","well_known_bundle":"https://pith.science/.well-known/pith/SM3VX2MV65FT6YJ6Y6BVGZXEMK/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2022:SM3VX2MV65FT6YJ6Y6BVGZXEMK","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"53cd8444bfbb5c35deffcc5af5e8fe57ef6926bdc2e5d1d74aa1dd4f7e1531c7","cross_cats_sorted":["cs.AI"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CV","submitted_at":"2022-03-21T10:20:04Z","title_canon_sha256":"18886b4266bfefed98b8f95a4c2d2f782940a4d62c84665eac17d8dd133c3bcb"},"schema_version":"1.0","source":{"id":"2203.10852","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2203.10852","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"arxiv_version","alias_value":"2203.10852v1","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2203.10852","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"pith_short_12","alias_value":"SM3VX2MV65FT","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"pith_short_16","alias_value":"SM3VX2MV65FT6YJ6","created_at":"2026-07-05T04:06:57Z"},{"alias_kind":"pith_short_8","alias_value":"SM3VX2MV","created_at":"2026-07-05T04:06:57Z"}],"graph_snapshots":[{"event_id":"sha256:596d9fbf4e4cdae1f62fb1e49cce909d4cf7148cc46fee4518d5ac5b2439361a","target":"graph","created_at":"2026-07-05T04:06:57Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2203.10852/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"The isocitrate dehydrogenase (IDH) gene mutation is an essential biomarker for the diagnosis and prognosis of glioma. It is promising to better predict glioma genotype by integrating focal tumor image and geometric features with brain network features derived from MRI. Convolutions neural networks show reasonable performance in predicting IDH mutation, which, however, cannot learn from non-Euclidean data, e.g., geometric and network data. In this study, we propose a multi-modal learning framework using three separate encoders to extract features of focal tumor image, tumor geometrics and globa","authors_text":"Carola-Bibiane Sch\\\"onlieb, Chao Li, Lei Zhu, Lipei Zhang, Stephen J. Price, Xi Chen, Yiran Wei","cross_cats":["cs.AI"],"headline":"","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CV","submitted_at":"2022-03-21T10:20:04Z","title":"Multi-modal learning for predicting the genotype of glioma"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2203.10852","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:faf293151dd1b86cfbbd4d8e154a502e37da2bbc3ce136b499c71aee4cc71ccf","target":"record","created_at":"2026-07-05T04:06:57Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"53cd8444bfbb5c35deffcc5af5e8fe57ef6926bdc2e5d1d74aa1dd4f7e1531c7","cross_cats_sorted":["cs.AI"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CV","submitted_at":"2022-03-21T10:20:04Z","title_canon_sha256":"18886b4266bfefed98b8f95a4c2d2f782940a4d62c84665eac17d8dd133c3bcb"},"schema_version":"1.0","source":{"id":"2203.10852","kind":"arxiv","version":1}},"canonical_sha256":"93375be995f74b3f613ec7835366e4628da4963c0fd28966fa9aac4f6300ae35","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"93375be995f74b3f613ec7835366e4628da4963c0fd28966fa9aac4f6300ae35","first_computed_at":"2026-07-05T04:06:57.985063Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T04:06:57.985063Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"Jkjm/n2gXFpU080EzqbMZQxz71/LCsYFyb4hz9DPNcCU6ZHy4Zsj0rYe/V5q5TrRppexcK1Z5hXFvEViobgeBg==","signature_status":"signed_v1","signed_at":"2026-07-05T04:06:57.985497Z","signed_message":"canonical_sha256_bytes"},"source_id":"2203.10852","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:faf293151dd1b86cfbbd4d8e154a502e37da2bbc3ce136b499c71aee4cc71ccf","sha256:596d9fbf4e4cdae1f62fb1e49cce909d4cf7148cc46fee4518d5ac5b2439361a"],"state_sha256":"8716c1ce89c6287b1388799c151a644c87ae2c71c331cad0ec61d3d241188f1f"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"/0XA8i9JQaEH7w8Sd1xF7vc8vV7mwpPJGr6F0ei/m/Mxu9FSHTzyLWH/fVJiqstpbSXmIPOrwsokvlEL3i8vBA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-14T01:29:49.526541Z","bundle_sha256":"09dce69e902704ec2602214d3f7695268539717e05c06d28be836d1d2fe7224d"}}