{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2025:T22UNPH75WIOOKEGHN6TXPSWFB","short_pith_number":"pith:T22UNPH7","canonical_record":{"source":{"id":"2506.20205","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.bio-ph","submitted_at":"2025-06-25T07:49:43Z","cross_cats_sorted":[],"title_canon_sha256":"37959119851c0f31236abddcc3cb12b4bfbfa3b893527c9e6cf77192d98b6da6","abstract_canon_sha256":"3738ce8c6483f170c06ebb26eac772dbc442886428fa70fc74d5160375d3a5ea"},"schema_version":"1.0"},"canonical_sha256":"9eb546bcffed90e728863b7d3bbe56284e3fc0fb9b09271ea53493c69f6ce837","source":{"kind":"arxiv","id":"2506.20205","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2506.20205","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"arxiv_version","alias_value":"2506.20205v1","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2506.20205","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"pith_short_12","alias_value":"T22UNPH75WIO","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"pith_short_16","alias_value":"T22UNPH75WIOOKEG","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"pith_short_8","alias_value":"T22UNPH7","created_at":"2026-06-23T01:11:56Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2025:T22UNPH75WIOOKEGHN6TXPSWFB","target":"record","payload":{"canonical_record":{"source":{"id":"2506.20205","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.bio-ph","submitted_at":"2025-06-25T07:49:43Z","cross_cats_sorted":[],"title_canon_sha256":"37959119851c0f31236abddcc3cb12b4bfbfa3b893527c9e6cf77192d98b6da6","abstract_canon_sha256":"3738ce8c6483f170c06ebb26eac772dbc442886428fa70fc74d5160375d3a5ea"},"schema_version":"1.0"},"canonical_sha256":"9eb546bcffed90e728863b7d3bbe56284e3fc0fb9b09271ea53493c69f6ce837","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-06-23T01:11:56.107655Z","signature_b64":"JH91zsQ9WIDLDI8DFtJdjgZlEwfvvOSvXDRNflfmQJLFIb1GJuvgGftpBeqrUonPYfMMpPQsERp6s4huP/CTBQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"9eb546bcffed90e728863b7d3bbe56284e3fc0fb9b09271ea53493c69f6ce837","last_reissued_at":"2026-06-23T01:11:56.107042Z","signature_status":"signed_v1","first_computed_at":"2026-06-23T01:11:56.107042Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2506.20205","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-06-23T01:11:56Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"/bbrKAKJDDjUHyS63IOidm8v9TH3pvURPgvzMYbake6JU2rP8u0gQt5PO13n5RBpPeUpVc4aby8M1sInbGP8Cg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-28T09:39:43.492487Z"},"content_sha256":"a67a7204cec8fcb540c44a55c4c340edbc10a506db730ba143f8b355dedc03c8","schema_version":"1.0","event_id":"sha256:a67a7204cec8fcb540c44a55c4c340edbc10a506db730ba143f8b355dedc03c8"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2025:T22UNPH75WIOOKEGHN6TXPSWFB","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Phenylalanine modification in plasma-driven biocatalysis revealed by solvent accessibility and reactive dynamics in combination with protein mass spectrometry","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Christoph Jung, Hanna-Friederike Poggemann, Julia E. Bandow, Sabrina Klopsch, Simon Homann, Sina Sch\\\"akermann, Tim Dirks, Timo Jacob","submitted_at":"2025-06-25T07:49:43Z","abstract_excerpt":"Biocatalysis is an emerging field that provides an environmentally friendly alternative to conventional catalysis, but still it faces some challenges. One of the major difficulties for biocatalysts that require reactive species like H2O2 as co-substrates lies in the concentration of these reactive species. On the one hand, they are used as reactants, but on the other hand, they inactivate the enzymes at high concentrations. When utilizing non-thermal plasma to deliver H2O2 for biocatalysis, it is essential to understand the potential interactions between plasma-generated species (PGS) and enzy"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2506.20205","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2506.20205/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-06-23T01:11:56Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"6aT8rP9XXL+vW59sy+b46qMbswKezgoMS7TAgpLK1iIaWJJWrHvnESgugx7NP+W4uhtdaZ5w2bvtEB2frLG4Aw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-28T09:39:43.492852Z"},"content_sha256":"e9cbf1ff5ac05953a718436d073847fcdd2a33d16a67895488318740286d1c87","schema_version":"1.0","event_id":"sha256:e9cbf1ff5ac05953a718436d073847fcdd2a33d16a67895488318740286d1c87"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/T22UNPH75WIOOKEGHN6TXPSWFB/bundle.json","state_url":"https://pith.science/pith/T22UNPH75WIOOKEGHN6TXPSWFB/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/T22UNPH75WIOOKEGHN6TXPSWFB/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-28T09:39:43Z","links":{"resolver":"https://pith.science/pith/T22UNPH75WIOOKEGHN6TXPSWFB","bundle":"https://pith.science/pith/T22UNPH75WIOOKEGHN6TXPSWFB/bundle.json","state":"https://pith.science/pith/T22UNPH75WIOOKEGHN6TXPSWFB/state.json","well_known_bundle":"https://pith.science/.well-known/pith/T22UNPH75WIOOKEGHN6TXPSWFB/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2025:T22UNPH75WIOOKEGHN6TXPSWFB","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"3738ce8c6483f170c06ebb26eac772dbc442886428fa70fc74d5160375d3a5ea","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.bio-ph","submitted_at":"2025-06-25T07:49:43Z","title_canon_sha256":"37959119851c0f31236abddcc3cb12b4bfbfa3b893527c9e6cf77192d98b6da6"},"schema_version":"1.0","source":{"id":"2506.20205","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2506.20205","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"arxiv_version","alias_value":"2506.20205v1","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2506.20205","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"pith_short_12","alias_value":"T22UNPH75WIO","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"pith_short_16","alias_value":"T22UNPH75WIOOKEG","created_at":"2026-06-23T01:11:56Z"},{"alias_kind":"pith_short_8","alias_value":"T22UNPH7","created_at":"2026-06-23T01:11:56Z"}],"graph_snapshots":[{"event_id":"sha256:e9cbf1ff5ac05953a718436d073847fcdd2a33d16a67895488318740286d1c87","target":"graph","created_at":"2026-06-23T01:11:56Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2506.20205/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Biocatalysis is an emerging field that provides an environmentally friendly alternative to conventional catalysis, but still it faces some challenges. One of the major difficulties for biocatalysts that require reactive species like H2O2 as co-substrates lies in the concentration of these reactive species. On the one hand, they are used as reactants, but on the other hand, they inactivate the enzymes at high concentrations. When utilizing non-thermal plasma to deliver H2O2 for biocatalysis, it is essential to understand the potential interactions between plasma-generated species (PGS) and enzy","authors_text":"Christoph Jung, Hanna-Friederike Poggemann, Julia E. Bandow, Sabrina Klopsch, Simon Homann, Sina Sch\\\"akermann, Tim Dirks, Timo Jacob","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.bio-ph","submitted_at":"2025-06-25T07:49:43Z","title":"Phenylalanine modification in plasma-driven biocatalysis revealed by solvent accessibility and reactive dynamics in combination with protein mass spectrometry"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2506.20205","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:a67a7204cec8fcb540c44a55c4c340edbc10a506db730ba143f8b355dedc03c8","target":"record","created_at":"2026-06-23T01:11:56Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"3738ce8c6483f170c06ebb26eac772dbc442886428fa70fc74d5160375d3a5ea","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.bio-ph","submitted_at":"2025-06-25T07:49:43Z","title_canon_sha256":"37959119851c0f31236abddcc3cb12b4bfbfa3b893527c9e6cf77192d98b6da6"},"schema_version":"1.0","source":{"id":"2506.20205","kind":"arxiv","version":1}},"canonical_sha256":"9eb546bcffed90e728863b7d3bbe56284e3fc0fb9b09271ea53493c69f6ce837","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"9eb546bcffed90e728863b7d3bbe56284e3fc0fb9b09271ea53493c69f6ce837","first_computed_at":"2026-06-23T01:11:56.107042Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-06-23T01:11:56.107042Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"JH91zsQ9WIDLDI8DFtJdjgZlEwfvvOSvXDRNflfmQJLFIb1GJuvgGftpBeqrUonPYfMMpPQsERp6s4huP/CTBQ==","signature_status":"signed_v1","signed_at":"2026-06-23T01:11:56.107655Z","signed_message":"canonical_sha256_bytes"},"source_id":"2506.20205","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:a67a7204cec8fcb540c44a55c4c340edbc10a506db730ba143f8b355dedc03c8","sha256:e9cbf1ff5ac05953a718436d073847fcdd2a33d16a67895488318740286d1c87"],"state_sha256":"ed99d85213e26f1dd87cc7026b6e8025adbaee1b7ea69f9bdf3ddf08bb8e4ddb"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Gp640V8cYqoEFlZAkaGzIgY952H2Hpl/OlAbpypst5qPGSsYBBbOuq9iXXMk27CkrpQKK2lnb/t3oIfgTjyLCQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-28T09:39:43.494775Z","bundle_sha256":"a4956da8356a11e43ecf06566138034c2bafddd5c35d60633295966f87ebafe3"}}