{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2014:UM5ZSOI6CLDPOCR2S5XTWBWV7W","short_pith_number":"pith:UM5ZSOI6","schema_version":"1.0","canonical_sha256":"a33b99391e12c6f70a3a976f3b06d5fd82e43aa7af61c49f9bf0f4b88c1c5249","source":{"kind":"arxiv","id":"1403.1876","version":1},"attestation_state":"computed","paper":{"title":"Consistent Testing for Recurrent Genomic Aberrations","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.QM","stat.TH"],"primary_cat":"math.ST","authors_text":"Andrew B. Nobel, Fred A. Wright, Vonn Walter","submitted_at":"2014-03-07T21:03:08Z","abstract_excerpt":"Genomic aberrations, such as somatic copy number alterations, are frequently observed in tumor tissue. Recurrent aberrations, occurring in the same region across multiple subjects, are of interest because they may highlight genes associated with tumor development or progression. A number of tools have been proposed to assess the statistical significance of recurrent DNA copy number aberrations, but their statistical properties have not been carefully studied. Cyclic shift testing, a permutation procedure using independent random shifts of genomic marker observations on the genome, has been pro"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1403.1876","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"math.ST","submitted_at":"2014-03-07T21:03:08Z","cross_cats_sorted":["q-bio.QM","stat.TH"],"title_canon_sha256":"547239e3d2a3ccc6a23af0781b938cf9ce7876d2c1f7b3b950b41debb9a89349","abstract_canon_sha256":"03a9782ebcd259aeb60e0c0899743cf23eae4564975285396a04c0e10b8cb353"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T02:56:51.363323Z","signature_b64":"f7x9Vfg+JWoDKT5Zx47Scdd2oqIKbdWbq7DlkjvnQvEFjSovFsFwg9U4HVCHRQnR61cp0ZFvM8ppfYaBB19UDQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"a33b99391e12c6f70a3a976f3b06d5fd82e43aa7af61c49f9bf0f4b88c1c5249","last_reissued_at":"2026-05-18T02:56:51.362873Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T02:56:51.362873Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Consistent Testing for Recurrent Genomic Aberrations","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.QM","stat.TH"],"primary_cat":"math.ST","authors_text":"Andrew B. Nobel, Fred A. Wright, Vonn Walter","submitted_at":"2014-03-07T21:03:08Z","abstract_excerpt":"Genomic aberrations, such as somatic copy number alterations, are frequently observed in tumor tissue. Recurrent aberrations, occurring in the same region across multiple subjects, are of interest because they may highlight genes associated with tumor development or progression. A number of tools have been proposed to assess the statistical significance of recurrent DNA copy number aberrations, but their statistical properties have not been carefully studied. Cyclic shift testing, a permutation procedure using independent random shifts of genomic marker observations on the genome, has been pro"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1403.1876","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1403.1876","created_at":"2026-05-18T02:56:51.362939+00:00"},{"alias_kind":"arxiv_version","alias_value":"1403.1876v1","created_at":"2026-05-18T02:56:51.362939+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1403.1876","created_at":"2026-05-18T02:56:51.362939+00:00"},{"alias_kind":"pith_short_12","alias_value":"UM5ZSOI6CLDP","created_at":"2026-05-18T12:28:52.271510+00:00"},{"alias_kind":"pith_short_16","alias_value":"UM5ZSOI6CLDPOCR2","created_at":"2026-05-18T12:28:52.271510+00:00"},{"alias_kind":"pith_short_8","alias_value":"UM5ZSOI6","created_at":"2026-05-18T12:28:52.271510+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/UM5ZSOI6CLDPOCR2S5XTWBWV7W","json":"https://pith.science/pith/UM5ZSOI6CLDPOCR2S5XTWBWV7W.json","graph_json":"https://pith.science/api/pith-number/UM5ZSOI6CLDPOCR2S5XTWBWV7W/graph.json","events_json":"https://pith.science/api/pith-number/UM5ZSOI6CLDPOCR2S5XTWBWV7W/events.json","paper":"https://pith.science/paper/UM5ZSOI6"},"agent_actions":{"view_html":"https://pith.science/pith/UM5ZSOI6CLDPOCR2S5XTWBWV7W","download_json":"https://pith.science/pith/UM5ZSOI6CLDPOCR2S5XTWBWV7W.json","view_paper":"https://pith.science/paper/UM5ZSOI6","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1403.1876&json=true","fetch_graph":"https://pith.science/api/pith-number/UM5ZSOI6CLDPOCR2S5XTWBWV7W/graph.json","fetch_events":"https://pith.science/api/pith-number/UM5ZSOI6CLDPOCR2S5XTWBWV7W/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/UM5ZSOI6CLDPOCR2S5XTWBWV7W/action/timestamp_anchor","attest_storage":"https://pith.science/pith/UM5ZSOI6CLDPOCR2S5XTWBWV7W/action/storage_attestation","attest_author":"https://pith.science/pith/UM5ZSOI6CLDPOCR2S5XTWBWV7W/action/author_attestation","sign_citation":"https://pith.science/pith/UM5ZSOI6CLDPOCR2S5XTWBWV7W/action/citation_signature","submit_replication":"https://pith.science/pith/UM5ZSOI6CLDPOCR2S5XTWBWV7W/action/replication_record"}},"created_at":"2026-05-18T02:56:51.362939+00:00","updated_at":"2026-05-18T02:56:51.362939+00:00"}