{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2012:VC764RBTU34QVEMLOEOJBB6M3S","short_pith_number":"pith:VC764RBT","schema_version":"1.0","canonical_sha256":"a8bfee4433a6f90a918b711c9087ccdc9a12176e46501cd6015e8d55a81b46cb","source":{"kind":"arxiv","id":"1202.0570","version":1},"attestation_state":"computed","paper":{"title":"Biomimetic emulsions reveal the effect of homeostatic pressure on cell-cell adhesion","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Ivane Jorjadze, Jasna Brujic, Lea-Laetitia Pontani, Virgile Viasnoff","submitted_at":"2012-02-02T21:56:55Z","abstract_excerpt":"Cell-cell contacts in tissues are continuously subject to mechanical forces due to homeostatic pressure and active cytoskeleton dynamics. While much is known about the molecular pathways of adhesion, the role of mechanics is less well understood. To isolate the role of pressure we present a dense packing of functionalized emulsion droplets in which surface interactions are tuned to mimic those of real cells. By visualizing the microstructure in 3D we find that a threshold compression force is necessary to overcome electrostatic repulsion and surface elasticity and establish protein-mediated ad"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1202.0570","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2012-02-02T21:56:55Z","cross_cats_sorted":[],"title_canon_sha256":"4385626b5582f720dd94590a3f283d77e8f8c4a1e2f740f1b6527e563172e1c7","abstract_canon_sha256":"990bac3b61605ae74958c15322608d6c3de23ca15dde95e6f41dbb1a73a7ab5c"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:58:35.989793Z","signature_b64":"s+LRNFsogp0dQwQ0RDukgg+6xGq34qBp1FstA5bL2wIh3yLElkOBip3ENIcaymfDGAhHBKdcWojS60DlAyRzCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"a8bfee4433a6f90a918b711c9087ccdc9a12176e46501cd6015e8d55a81b46cb","last_reissued_at":"2026-05-18T01:58:35.989169Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:58:35.989169Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Biomimetic emulsions reveal the effect of homeostatic pressure on cell-cell adhesion","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Ivane Jorjadze, Jasna Brujic, Lea-Laetitia Pontani, Virgile Viasnoff","submitted_at":"2012-02-02T21:56:55Z","abstract_excerpt":"Cell-cell contacts in tissues are continuously subject to mechanical forces due to homeostatic pressure and active cytoskeleton dynamics. While much is known about the molecular pathways of adhesion, the role of mechanics is less well understood. To isolate the role of pressure we present a dense packing of functionalized emulsion droplets in which surface interactions are tuned to mimic those of real cells. By visualizing the microstructure in 3D we find that a threshold compression force is necessary to overcome electrostatic repulsion and surface elasticity and establish protein-mediated ad"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1202.0570","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1202.0570","created_at":"2026-05-18T01:58:35.989262+00:00"},{"alias_kind":"arxiv_version","alias_value":"1202.0570v1","created_at":"2026-05-18T01:58:35.989262+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1202.0570","created_at":"2026-05-18T01:58:35.989262+00:00"},{"alias_kind":"pith_short_12","alias_value":"VC764RBTU34Q","created_at":"2026-05-18T12:27:25.539911+00:00"},{"alias_kind":"pith_short_16","alias_value":"VC764RBTU34QVEML","created_at":"2026-05-18T12:27:25.539911+00:00"},{"alias_kind":"pith_short_8","alias_value":"VC764RBT","created_at":"2026-05-18T12:27:25.539911+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/VC764RBTU34QVEMLOEOJBB6M3S","json":"https://pith.science/pith/VC764RBTU34QVEMLOEOJBB6M3S.json","graph_json":"https://pith.science/api/pith-number/VC764RBTU34QVEMLOEOJBB6M3S/graph.json","events_json":"https://pith.science/api/pith-number/VC764RBTU34QVEMLOEOJBB6M3S/events.json","paper":"https://pith.science/paper/VC764RBT"},"agent_actions":{"view_html":"https://pith.science/pith/VC764RBTU34QVEMLOEOJBB6M3S","download_json":"https://pith.science/pith/VC764RBTU34QVEMLOEOJBB6M3S.json","view_paper":"https://pith.science/paper/VC764RBT","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1202.0570&json=true","fetch_graph":"https://pith.science/api/pith-number/VC764RBTU34QVEMLOEOJBB6M3S/graph.json","fetch_events":"https://pith.science/api/pith-number/VC764RBTU34QVEMLOEOJBB6M3S/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/VC764RBTU34QVEMLOEOJBB6M3S/action/timestamp_anchor","attest_storage":"https://pith.science/pith/VC764RBTU34QVEMLOEOJBB6M3S/action/storage_attestation","attest_author":"https://pith.science/pith/VC764RBTU34QVEMLOEOJBB6M3S/action/author_attestation","sign_citation":"https://pith.science/pith/VC764RBTU34QVEMLOEOJBB6M3S/action/citation_signature","submit_replication":"https://pith.science/pith/VC764RBTU34QVEMLOEOJBB6M3S/action/replication_record"}},"created_at":"2026-05-18T01:58:35.989262+00:00","updated_at":"2026-05-18T01:58:35.989262+00:00"}