{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2009:VGVLAPKX53UPC77EHM7SXSWR7B","short_pith_number":"pith:VGVLAPKX","schema_version":"1.0","canonical_sha256":"a9aab03d57eee8f17fe43b3f2bcad1f85c7edc35929e5055e3a702fed41facce","source":{"kind":"arxiv","id":"0910.1499","version":1},"attestation_state":"computed","paper":{"title":"Non-destructive Imaging of Individual Bio-Molecules","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Conrad Escher, Hans-Werner Fink, Matthias Germann, Tatiana Latychevskaia","submitted_at":"2009-10-08T13:15:16Z","abstract_excerpt":"Radiation damage is considered to be the major problem that still prevents imaging an individual biological molecule for structural analysis. So far, all known mapping techniques using sufficient short wave-length radiation, be it X-rays or high energy electrons, circumvent this problem by averaging over many molecules. Averaging, however, leaves conformational details uncovered. Even the anticipated use of ultra-short but extremely bright X-ray bursts of a Free Electron Laser shall afford averaging over 10^6 molecules to arrive at atomic resolution. Here we present direct experimental evidenc"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"0910.1499","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2009-10-08T13:15:16Z","cross_cats_sorted":[],"title_canon_sha256":"a711ef4db4a2c6789fc44f55d2a7459a6675e547ce025a7cb59ea36816a3c798","abstract_canon_sha256":"3bc23e7b8e6698ade5ededdca984f449c1d25d6c29069f53a18ce3c1a67d6828"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T04:38:17.347089Z","signature_b64":"PhdNrnxoSXLizQUYhQS38Pszv9/acq4cwk6iH2oW1RHvENG/orOuAvi+u/k3W7rHyFZ4y49slddxFM0Z068rAA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"a9aab03d57eee8f17fe43b3f2bcad1f85c7edc35929e5055e3a702fed41facce","last_reissued_at":"2026-05-18T04:38:17.346469Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T04:38:17.346469Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Non-destructive Imaging of Individual Bio-Molecules","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Conrad Escher, Hans-Werner Fink, Matthias Germann, Tatiana Latychevskaia","submitted_at":"2009-10-08T13:15:16Z","abstract_excerpt":"Radiation damage is considered to be the major problem that still prevents imaging an individual biological molecule for structural analysis. So far, all known mapping techniques using sufficient short wave-length radiation, be it X-rays or high energy electrons, circumvent this problem by averaging over many molecules. Averaging, however, leaves conformational details uncovered. Even the anticipated use of ultra-short but extremely bright X-ray bursts of a Free Electron Laser shall afford averaging over 10^6 molecules to arrive at atomic resolution. Here we present direct experimental evidenc"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"0910.1499","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"0910.1499","created_at":"2026-05-18T04:38:17.346568+00:00"},{"alias_kind":"arxiv_version","alias_value":"0910.1499v1","created_at":"2026-05-18T04:38:17.346568+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.0910.1499","created_at":"2026-05-18T04:38:17.346568+00:00"},{"alias_kind":"pith_short_12","alias_value":"VGVLAPKX53UP","created_at":"2026-05-18T12:26:02.257875+00:00"},{"alias_kind":"pith_short_16","alias_value":"VGVLAPKX53UPC77E","created_at":"2026-05-18T12:26:02.257875+00:00"},{"alias_kind":"pith_short_8","alias_value":"VGVLAPKX","created_at":"2026-05-18T12:26:02.257875+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/VGVLAPKX53UPC77EHM7SXSWR7B","json":"https://pith.science/pith/VGVLAPKX53UPC77EHM7SXSWR7B.json","graph_json":"https://pith.science/api/pith-number/VGVLAPKX53UPC77EHM7SXSWR7B/graph.json","events_json":"https://pith.science/api/pith-number/VGVLAPKX53UPC77EHM7SXSWR7B/events.json","paper":"https://pith.science/paper/VGVLAPKX"},"agent_actions":{"view_html":"https://pith.science/pith/VGVLAPKX53UPC77EHM7SXSWR7B","download_json":"https://pith.science/pith/VGVLAPKX53UPC77EHM7SXSWR7B.json","view_paper":"https://pith.science/paper/VGVLAPKX","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=0910.1499&json=true","fetch_graph":"https://pith.science/api/pith-number/VGVLAPKX53UPC77EHM7SXSWR7B/graph.json","fetch_events":"https://pith.science/api/pith-number/VGVLAPKX53UPC77EHM7SXSWR7B/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/VGVLAPKX53UPC77EHM7SXSWR7B/action/timestamp_anchor","attest_storage":"https://pith.science/pith/VGVLAPKX53UPC77EHM7SXSWR7B/action/storage_attestation","attest_author":"https://pith.science/pith/VGVLAPKX53UPC77EHM7SXSWR7B/action/author_attestation","sign_citation":"https://pith.science/pith/VGVLAPKX53UPC77EHM7SXSWR7B/action/citation_signature","submit_replication":"https://pith.science/pith/VGVLAPKX53UPC77EHM7SXSWR7B/action/replication_record"}},"created_at":"2026-05-18T04:38:17.346568+00:00","updated_at":"2026-05-18T04:38:17.346568+00:00"}