{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2023:XACGZOUSMING3W6GB6RARYFVTN","short_pith_number":"pith:XACGZOUS","canonical_record":{"source":{"id":"2301.04114","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"quant-ph","submitted_at":"2023-01-10T18:32:47Z","cross_cats_sorted":[],"title_canon_sha256":"e4cf451ba13a974e8cf396c669d42d9778d2cd514d838f7b6848be88c825eb46","abstract_canon_sha256":"5494bfefab4cbca91b3f4e5a4b83c96b99cf1cb03c43093023f3e4a4bb2600cc"},"schema_version":"1.0"},"canonical_sha256":"b8046cba92621a6ddbc60fa208e0b59b55dfa23ee1734a2ac649261b1f888ca0","source":{"kind":"arxiv","id":"2301.04114","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2301.04114","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"arxiv_version","alias_value":"2301.04114v1","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2301.04114","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"pith_short_12","alias_value":"XACGZOUSMING","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"pith_short_16","alias_value":"XACGZOUSMING3W6G","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"pith_short_8","alias_value":"XACGZOUS","created_at":"2026-07-05T07:51:25Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2023:XACGZOUSMING3W6GB6RARYFVTN","target":"record","payload":{"canonical_record":{"source":{"id":"2301.04114","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"quant-ph","submitted_at":"2023-01-10T18:32:47Z","cross_cats_sorted":[],"title_canon_sha256":"e4cf451ba13a974e8cf396c669d42d9778d2cd514d838f7b6848be88c825eb46","abstract_canon_sha256":"5494bfefab4cbca91b3f4e5a4b83c96b99cf1cb03c43093023f3e4a4bb2600cc"},"schema_version":"1.0"},"canonical_sha256":"b8046cba92621a6ddbc60fa208e0b59b55dfa23ee1734a2ac649261b1f888ca0","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T07:51:25.909090Z","signature_b64":"3CGDi6KrmzprOxbCt6QTMtqAZDKKcVb9noGARwODsJknvWbMiVclX8rT1nnM4HZkkIp00ENOVPhnXKc+JmuXDg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"b8046cba92621a6ddbc60fa208e0b59b55dfa23ee1734a2ac649261b1f888ca0","last_reissued_at":"2026-07-05T07:51:25.908544Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T07:51:25.908544Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2301.04114","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T07:51:25Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"sKYQtS8MkTYygbkcsTAs8pQsRmH6nWXhNqk8v8FKHlxlzvexA7cccuI35P2G/KLb6MgMnftwgGEFlUlbJTMiBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-07T08:01:45.932291Z"},"content_sha256":"7fff40b4eb151a8efe4145e0f58366e8bd45c087e0fa1ac164287392069f9673","schema_version":"1.0","event_id":"sha256:7fff40b4eb151a8efe4145e0f58366e8bd45c087e0fa1ac164287392069f9673"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2023:XACGZOUSMING3W6GB6RARYFVTN","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Drug design on quantum computers","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"quant-ph","authors_text":"Alan Aspuru-Guzik, Christofer S. Tautermann, Clemens Utschig-Utschig, Elica Kyoseva, Horst Weiss, Leticia Gonzalez, Markus Oppel, Matthias Degroote, Michael Streif, Nathan Wiebe, Nicholas C. Rubin, Nikolaj Moll, Raffaele Santagati, Robert M. Parrish, Ryan Babbush","submitted_at":"2023-01-10T18:32:47Z","abstract_excerpt":"Quantum computers promise to impact industrial applications, for which quantum chemical calculations are required, by virtue of their high accuracy. This perspective explores the challenges and opportunities of applying quantum computers to drug design, discusses where they could transform industrial research and elaborates on what is needed to reach this goal."},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2301.04114","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2301.04114/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T07:51:25Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"k0QIrjYIJodF+fkSEf5JpXJo/H3RJwdEgMmqon9FRYiJmAwImH5Z9kj5GCz5AkzEuHHD74AAEM2XqLGwd+sMCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-07T08:01:45.932681Z"},"content_sha256":"b80eb7e4c627f5d5647e7f12941521fdda5938a11e14f563246a0474d5424c08","schema_version":"1.0","event_id":"sha256:b80eb7e4c627f5d5647e7f12941521fdda5938a11e14f563246a0474d5424c08"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/XACGZOUSMING3W6GB6RARYFVTN/bundle.json","state_url":"https://pith.science/pith/XACGZOUSMING3W6GB6RARYFVTN/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/XACGZOUSMING3W6GB6RARYFVTN/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-07T08:01:45Z","links":{"resolver":"https://pith.science/pith/XACGZOUSMING3W6GB6RARYFVTN","bundle":"https://pith.science/pith/XACGZOUSMING3W6GB6RARYFVTN/bundle.json","state":"https://pith.science/pith/XACGZOUSMING3W6GB6RARYFVTN/state.json","well_known_bundle":"https://pith.science/.well-known/pith/XACGZOUSMING3W6GB6RARYFVTN/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2023:XACGZOUSMING3W6GB6RARYFVTN","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"5494bfefab4cbca91b3f4e5a4b83c96b99cf1cb03c43093023f3e4a4bb2600cc","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"quant-ph","submitted_at":"2023-01-10T18:32:47Z","title_canon_sha256":"e4cf451ba13a974e8cf396c669d42d9778d2cd514d838f7b6848be88c825eb46"},"schema_version":"1.0","source":{"id":"2301.04114","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2301.04114","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"arxiv_version","alias_value":"2301.04114v1","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2301.04114","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"pith_short_12","alias_value":"XACGZOUSMING","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"pith_short_16","alias_value":"XACGZOUSMING3W6G","created_at":"2026-07-05T07:51:25Z"},{"alias_kind":"pith_short_8","alias_value":"XACGZOUS","created_at":"2026-07-05T07:51:25Z"}],"graph_snapshots":[{"event_id":"sha256:b80eb7e4c627f5d5647e7f12941521fdda5938a11e14f563246a0474d5424c08","target":"graph","created_at":"2026-07-05T07:51:25Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2301.04114/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Quantum computers promise to impact industrial applications, for which quantum chemical calculations are required, by virtue of their high accuracy. This perspective explores the challenges and opportunities of applying quantum computers to drug design, discusses where they could transform industrial research and elaborates on what is needed to reach this goal.","authors_text":"Alan Aspuru-Guzik, Christofer S. Tautermann, Clemens Utschig-Utschig, Elica Kyoseva, Horst Weiss, Leticia Gonzalez, Markus Oppel, Matthias Degroote, Michael Streif, Nathan Wiebe, Nicholas C. Rubin, Nikolaj Moll, Raffaele Santagati, Robert M. Parrish, Ryan Babbush","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"quant-ph","submitted_at":"2023-01-10T18:32:47Z","title":"Drug design on quantum computers"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2301.04114","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:7fff40b4eb151a8efe4145e0f58366e8bd45c087e0fa1ac164287392069f9673","target":"record","created_at":"2026-07-05T07:51:25Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"5494bfefab4cbca91b3f4e5a4b83c96b99cf1cb03c43093023f3e4a4bb2600cc","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"quant-ph","submitted_at":"2023-01-10T18:32:47Z","title_canon_sha256":"e4cf451ba13a974e8cf396c669d42d9778d2cd514d838f7b6848be88c825eb46"},"schema_version":"1.0","source":{"id":"2301.04114","kind":"arxiv","version":1}},"canonical_sha256":"b8046cba92621a6ddbc60fa208e0b59b55dfa23ee1734a2ac649261b1f888ca0","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"b8046cba92621a6ddbc60fa208e0b59b55dfa23ee1734a2ac649261b1f888ca0","first_computed_at":"2026-07-05T07:51:25.908544Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T07:51:25.908544Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"3CGDi6KrmzprOxbCt6QTMtqAZDKKcVb9noGARwODsJknvWbMiVclX8rT1nnM4HZkkIp00ENOVPhnXKc+JmuXDg==","signature_status":"signed_v1","signed_at":"2026-07-05T07:51:25.909090Z","signed_message":"canonical_sha256_bytes"},"source_id":"2301.04114","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:7fff40b4eb151a8efe4145e0f58366e8bd45c087e0fa1ac164287392069f9673","sha256:b80eb7e4c627f5d5647e7f12941521fdda5938a11e14f563246a0474d5424c08"],"state_sha256":"da3c8acd10f383603a3653717cbb52c28d39b0a8e3232a4829a2c9af82e5839d"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"gUKfLj0wirBjT2kqT/GaDT/AyODKr7E5uFqu0WXWKa4clICQ4DoWd724mjXLxf6BJ/lMravFrvufFra8orCNBw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-07T08:01:45.934708Z","bundle_sha256":"e6aaff3d3261da17a31ef42608225150ff5334ec9d68ffd61cd83ac131cc6aa3"}}