{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2026:XEEQGAFUWIEZTMQZKPYO4GUVO2","short_pith_number":"pith:XEEQGAFU","schema_version":"1.0","canonical_sha256":"b9090300b4b20999b21953f0ee1a957693e08725c8873d6a39d78af202723388","source":{"kind":"arxiv","id":"2606.18523","version":1},"attestation_state":"computed","paper":{"title":"DART: A design-aware microfluidic chip paradigm for real-time live-cell image analysis","license":"http://creativecommons.org/licenses/by-sa/4.0/","headline":"","cross_cats":["cs.CV"],"primary_cat":"q-bio.QM","authors_text":"Dietrich Kohlheyer, Hanno Scharr, Johannes Seiffarth, Katharina N\\\"oh, Lukas Scholtes, Matthias Pesch","submitted_at":"2026-06-16T22:38:19Z","abstract_excerpt":"High-throughput microfluidic live-cell imaging generates rich single-cell data. Yet semi-automated procedures for locating regions of interest (RoIs), each containing one cell population, and removing surrounding microfluidic structures from recorded images, scale with the number of RoIs. This prevents real-time image analysis and delays time-to-insight by hours to days. We introduce the Design-Aware and Real-Time capable (DART) paradigm for microfluidic cultivation chips, which aligns the CAD blueprint with the physical chip and thereby enables throughput-independent localization of all RoIs "},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"2606.18523","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-sa/4.0/","primary_cat":"q-bio.QM","submitted_at":"2026-06-16T22:38:19Z","cross_cats_sorted":["cs.CV"],"title_canon_sha256":"9634057dd3261b06c3431fdc9fd4047f07522cb54ba63cfece3faffce47a0bcf","abstract_canon_sha256":"f19a3938d959b08fbdc618a07b31ab653c0d455b096e3c14dec6d2c71a38766d"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-06-19T16:11:40.008063Z","signature_b64":"VbxuAYPzEDalikhNH5/u7i4v8naRWYBi0iy0O5bM6G/4jcUQ3f7kz5kpOD/BcqfvpdhOG3kTBq/OnSIS1V8PAA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"b9090300b4b20999b21953f0ee1a957693e08725c8873d6a39d78af202723388","last_reissued_at":"2026-06-19T16:11:40.007654Z","signature_status":"signed_v1","first_computed_at":"2026-06-19T16:11:40.007654Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"DART: A design-aware microfluidic chip paradigm for real-time live-cell image analysis","license":"http://creativecommons.org/licenses/by-sa/4.0/","headline":"","cross_cats":["cs.CV"],"primary_cat":"q-bio.QM","authors_text":"Dietrich Kohlheyer, Hanno Scharr, Johannes Seiffarth, Katharina N\\\"oh, Lukas Scholtes, Matthias Pesch","submitted_at":"2026-06-16T22:38:19Z","abstract_excerpt":"High-throughput microfluidic live-cell imaging generates rich single-cell data. Yet semi-automated procedures for locating regions of interest (RoIs), each containing one cell population, and removing surrounding microfluidic structures from recorded images, scale with the number of RoIs. This prevents real-time image analysis and delays time-to-insight by hours to days. We introduce the Design-Aware and Real-Time capable (DART) paradigm for microfluidic cultivation chips, which aligns the CAD blueprint with the physical chip and thereby enables throughput-independent localization of all RoIs "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2606.18523","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2606.18523/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"2606.18523","created_at":"2026-06-19T16:11:40.007719+00:00"},{"alias_kind":"arxiv_version","alias_value":"2606.18523v1","created_at":"2026-06-19T16:11:40.007719+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2606.18523","created_at":"2026-06-19T16:11:40.007719+00:00"},{"alias_kind":"pith_short_12","alias_value":"XEEQGAFUWIEZ","created_at":"2026-06-19T16:11:40.007719+00:00"},{"alias_kind":"pith_short_16","alias_value":"XEEQGAFUWIEZTMQZ","created_at":"2026-06-19T16:11:40.007719+00:00"},{"alias_kind":"pith_short_8","alias_value":"XEEQGAFU","created_at":"2026-06-19T16:11:40.007719+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/XEEQGAFUWIEZTMQZKPYO4GUVO2","json":"https://pith.science/pith/XEEQGAFUWIEZTMQZKPYO4GUVO2.json","graph_json":"https://pith.science/api/pith-number/XEEQGAFUWIEZTMQZKPYO4GUVO2/graph.json","events_json":"https://pith.science/api/pith-number/XEEQGAFUWIEZTMQZKPYO4GUVO2/events.json","paper":"https://pith.science/paper/XEEQGAFU"},"agent_actions":{"view_html":"https://pith.science/pith/XEEQGAFUWIEZTMQZKPYO4GUVO2","download_json":"https://pith.science/pith/XEEQGAFUWIEZTMQZKPYO4GUVO2.json","view_paper":"https://pith.science/paper/XEEQGAFU","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=2606.18523&json=true","fetch_graph":"https://pith.science/api/pith-number/XEEQGAFUWIEZTMQZKPYO4GUVO2/graph.json","fetch_events":"https://pith.science/api/pith-number/XEEQGAFUWIEZTMQZKPYO4GUVO2/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/XEEQGAFUWIEZTMQZKPYO4GUVO2/action/timestamp_anchor","attest_storage":"https://pith.science/pith/XEEQGAFUWIEZTMQZKPYO4GUVO2/action/storage_attestation","attest_author":"https://pith.science/pith/XEEQGAFUWIEZTMQZKPYO4GUVO2/action/author_attestation","sign_citation":"https://pith.science/pith/XEEQGAFUWIEZTMQZKPYO4GUVO2/action/citation_signature","submit_replication":"https://pith.science/pith/XEEQGAFUWIEZTMQZKPYO4GUVO2/action/replication_record"}},"created_at":"2026-06-19T16:11:40.007719+00:00","updated_at":"2026-06-19T16:11:40.007719+00:00"}