{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:ZDVQBOPIQFLZXBIAEBFMWWC2YS","short_pith_number":"pith:ZDVQBOPI","canonical_record":{"source":{"id":"1904.01192","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CE","submitted_at":"2019-04-02T03:28:58Z","cross_cats_sorted":[],"title_canon_sha256":"73276ac191572d37095e63519c8fe2d1943d35008f6f20fe5956c8c4dca50435","abstract_canon_sha256":"a7f675785b32b6d01108968b0a7f069bb73c6ab48e9809f231ac96d1dbf9406e"},"schema_version":"1.0"},"canonical_sha256":"c8eb00b9e881579b8500204acb585ac48c81b7d8a836fa0b265d5dfd95e66e6e","source":{"kind":"arxiv","id":"1904.01192","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1904.01192","created_at":"2026-05-17T23:49:35Z"},{"alias_kind":"arxiv_version","alias_value":"1904.01192v1","created_at":"2026-05-17T23:49:35Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1904.01192","created_at":"2026-05-17T23:49:35Z"},{"alias_kind":"pith_short_12","alias_value":"ZDVQBOPIQFLZ","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_16","alias_value":"ZDVQBOPIQFLZXBIA","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_8","alias_value":"ZDVQBOPI","created_at":"2026-05-18T12:33:33Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:ZDVQBOPIQFLZXBIAEBFMWWC2YS","target":"record","payload":{"canonical_record":{"source":{"id":"1904.01192","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CE","submitted_at":"2019-04-02T03:28:58Z","cross_cats_sorted":[],"title_canon_sha256":"73276ac191572d37095e63519c8fe2d1943d35008f6f20fe5956c8c4dca50435","abstract_canon_sha256":"a7f675785b32b6d01108968b0a7f069bb73c6ab48e9809f231ac96d1dbf9406e"},"schema_version":"1.0"},"canonical_sha256":"c8eb00b9e881579b8500204acb585ac48c81b7d8a836fa0b265d5dfd95e66e6e","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:49:35.614403Z","signature_b64":"fCp14hZgMqYeh5xPXVYS8PT/4VAPep9ZgatGCoRWw1qXF/8UAzMTZgUtB0OCRQcpUKkygpkEZgHk2cXrYwsuDA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"c8eb00b9e881579b8500204acb585ac48c81b7d8a836fa0b265d5dfd95e66e6e","last_reissued_at":"2026-05-17T23:49:35.613859Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:49:35.613859Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1904.01192","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:49:35Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"64H7m2oDmQCq/ANZyJNkP0NKb0xieWF4X+AUC4tAuUDGVWKlmx3Svfge6w2I+IPx2qn4T4QP2B8nE5qfPemLDA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-01T21:27:48.456805Z"},"content_sha256":"77665dea73b50d199ab72da6d9120d17fe58f8724a44a3b8631f06d423fba6db","schema_version":"1.0","event_id":"sha256:77665dea73b50d199ab72da6d9120d17fe58f8724a44a3b8631f06d423fba6db"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:ZDVQBOPIQFLZXBIAEBFMWWC2YS","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Biomechanical modeling and computer simulation of the brain during neurosurgery","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"cs.CE","authors_text":"A. Wittek, D. E. Hyde, G. Bourantas, G. R. Joldes, K. Miller, R. Kikinis, S. K. Warfield","submitted_at":"2019-04-02T03:28:58Z","abstract_excerpt":"Computational biomechanics of the brain for neurosurgery is an emerging area of research recently gaining in importance and practical applications. This review paper presents the contributions of the Intelligent Systems for Medicine Laboratory and it's collaborators to this field, discussing the modeling approaches adopted and the methods developed for obtaining the numerical solutions. We adopt a physics-based modeling approach, and describe the brain deformation in mechanical terms (such as displacements, strains and stresses), which can be computed using a biomechanical model, by solving a "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1904.01192","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:49:35Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"AlPl40PlCvv4u3WvIbi3U8MBQTq/mBkUBw6eMixrRf7XRIfB5/0Mb3mY3wzGbzdcR+/6f6hPx+STgcZBD8euCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-01T21:27:48.457149Z"},"content_sha256":"bfa989e5cb167d02c9bf4c6a2104b843a82f6c219b9233eaeba79090168fb8f9","schema_version":"1.0","event_id":"sha256:bfa989e5cb167d02c9bf4c6a2104b843a82f6c219b9233eaeba79090168fb8f9"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/ZDVQBOPIQFLZXBIAEBFMWWC2YS/bundle.json","state_url":"https://pith.science/pith/ZDVQBOPIQFLZXBIAEBFMWWC2YS/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/ZDVQBOPIQFLZXBIAEBFMWWC2YS/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-01T21:27:48Z","links":{"resolver":"https://pith.science/pith/ZDVQBOPIQFLZXBIAEBFMWWC2YS","bundle":"https://pith.science/pith/ZDVQBOPIQFLZXBIAEBFMWWC2YS/bundle.json","state":"https://pith.science/pith/ZDVQBOPIQFLZXBIAEBFMWWC2YS/state.json","well_known_bundle":"https://pith.science/.well-known/pith/ZDVQBOPIQFLZXBIAEBFMWWC2YS/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:ZDVQBOPIQFLZXBIAEBFMWWC2YS","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"a7f675785b32b6d01108968b0a7f069bb73c6ab48e9809f231ac96d1dbf9406e","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CE","submitted_at":"2019-04-02T03:28:58Z","title_canon_sha256":"73276ac191572d37095e63519c8fe2d1943d35008f6f20fe5956c8c4dca50435"},"schema_version":"1.0","source":{"id":"1904.01192","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1904.01192","created_at":"2026-05-17T23:49:35Z"},{"alias_kind":"arxiv_version","alias_value":"1904.01192v1","created_at":"2026-05-17T23:49:35Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1904.01192","created_at":"2026-05-17T23:49:35Z"},{"alias_kind":"pith_short_12","alias_value":"ZDVQBOPIQFLZ","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_16","alias_value":"ZDVQBOPIQFLZXBIA","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_8","alias_value":"ZDVQBOPI","created_at":"2026-05-18T12:33:33Z"}],"graph_snapshots":[{"event_id":"sha256:bfa989e5cb167d02c9bf4c6a2104b843a82f6c219b9233eaeba79090168fb8f9","target":"graph","created_at":"2026-05-17T23:49:35Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Computational biomechanics of the brain for neurosurgery is an emerging area of research recently gaining in importance and practical applications. This review paper presents the contributions of the Intelligent Systems for Medicine Laboratory and it's collaborators to this field, discussing the modeling approaches adopted and the methods developed for obtaining the numerical solutions. We adopt a physics-based modeling approach, and describe the brain deformation in mechanical terms (such as displacements, strains and stresses), which can be computed using a biomechanical model, by solving a ","authors_text":"A. Wittek, D. E. Hyde, G. Bourantas, G. R. Joldes, K. Miller, R. Kikinis, S. K. Warfield","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CE","submitted_at":"2019-04-02T03:28:58Z","title":"Biomechanical modeling and computer simulation of the brain during neurosurgery"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1904.01192","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:77665dea73b50d199ab72da6d9120d17fe58f8724a44a3b8631f06d423fba6db","target":"record","created_at":"2026-05-17T23:49:35Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"a7f675785b32b6d01108968b0a7f069bb73c6ab48e9809f231ac96d1dbf9406e","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CE","submitted_at":"2019-04-02T03:28:58Z","title_canon_sha256":"73276ac191572d37095e63519c8fe2d1943d35008f6f20fe5956c8c4dca50435"},"schema_version":"1.0","source":{"id":"1904.01192","kind":"arxiv","version":1}},"canonical_sha256":"c8eb00b9e881579b8500204acb585ac48c81b7d8a836fa0b265d5dfd95e66e6e","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"c8eb00b9e881579b8500204acb585ac48c81b7d8a836fa0b265d5dfd95e66e6e","first_computed_at":"2026-05-17T23:49:35.613859Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:49:35.613859Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"fCp14hZgMqYeh5xPXVYS8PT/4VAPep9ZgatGCoRWw1qXF/8UAzMTZgUtB0OCRQcpUKkygpkEZgHk2cXrYwsuDA==","signature_status":"signed_v1","signed_at":"2026-05-17T23:49:35.614403Z","signed_message":"canonical_sha256_bytes"},"source_id":"1904.01192","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:77665dea73b50d199ab72da6d9120d17fe58f8724a44a3b8631f06d423fba6db","sha256:bfa989e5cb167d02c9bf4c6a2104b843a82f6c219b9233eaeba79090168fb8f9"],"state_sha256":"4dcf48b9421f256de96903d344a6fd5561bb07f231863c1d2182566e2f6c4dd1"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"i3/igBTtqSTqM5w41FEikRgfGP5FHv3yJg8FqXEJg18BNiD9nul47dSisD5SAhFawiF1cpQJoEaNjS5R7pCdCA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-01T21:27:48.459018Z","bundle_sha256":"18855d80a16f5acfee8ee941c8b6e60f0653848b4373c18b0b6245caeb8407da"}}