{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:ZZCE7GGKUVMXWTCWR7JMFLWACR","short_pith_number":"pith:ZZCE7GGK","canonical_record":{"source":{"id":"1906.11039","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-06-17T16:15:30Z","cross_cats_sorted":[],"title_canon_sha256":"1d323304028c880ef5dcffbb81ec1f6a151fdc7a21bdc22488ea871bc76a2fe2","abstract_canon_sha256":"2aa3ca5ba81a7fdf67327bd2060021d587c45f154fb6943cdf0de2ffa9cee250"},"schema_version":"1.0"},"canonical_sha256":"ce444f98caa5597b4c568fd2c2aec01479bde6462abf927320198014ed05dc08","source":{"kind":"arxiv","id":"1906.11039","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1906.11039","created_at":"2026-05-17T23:41:52Z"},{"alias_kind":"arxiv_version","alias_value":"1906.11039v3","created_at":"2026-05-17T23:41:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1906.11039","created_at":"2026-05-17T23:41:52Z"},{"alias_kind":"pith_short_12","alias_value":"ZZCE7GGKUVMX","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_16","alias_value":"ZZCE7GGKUVMXWTCW","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_8","alias_value":"ZZCE7GGK","created_at":"2026-05-18T12:33:33Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:ZZCE7GGKUVMXWTCWR7JMFLWACR","target":"record","payload":{"canonical_record":{"source":{"id":"1906.11039","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-06-17T16:15:30Z","cross_cats_sorted":[],"title_canon_sha256":"1d323304028c880ef5dcffbb81ec1f6a151fdc7a21bdc22488ea871bc76a2fe2","abstract_canon_sha256":"2aa3ca5ba81a7fdf67327bd2060021d587c45f154fb6943cdf0de2ffa9cee250"},"schema_version":"1.0"},"canonical_sha256":"ce444f98caa5597b4c568fd2c2aec01479bde6462abf927320198014ed05dc08","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:41:52.714411Z","signature_b64":"t/GFZoSlIxK4xv5yfVlLCPUBykY9t9/5g4HS0aOph7lz60cuomASpq46sFZFk8IYr+qcprk7VMCZuFa6kBV1BQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"ce444f98caa5597b4c568fd2c2aec01479bde6462abf927320198014ed05dc08","last_reissued_at":"2026-05-17T23:41:52.713893Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:41:52.713893Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1906.11039","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:41:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"WTOKlYxplBD6ohPgjU7czAK9KmHVpsun3/QYuwExGWEJDz8EbS3ZUjhVl4vSdW5VBcbywGAC3I9W4ibNmktuCQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-21T22:46:21.163582Z"},"content_sha256":"da0a63606b667cb470bc864a3067c9ac205b4dd5d2d063bb97035a368aee7ec3","schema_version":"1.0","event_id":"sha256:da0a63606b667cb470bc864a3067c9ac205b4dd5d2d063bb97035a368aee7ec3"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:ZZCE7GGKUVMXWTCWR7JMFLWACR","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Kinetic models with non-local sensing determining cell polarization and speed according to independent cues","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.CB","authors_text":"Luigi Preziosi, Nadia Loy","submitted_at":"2019-06-17T16:15:30Z","abstract_excerpt":"Cells move by run and tumble, a kind of dynamics in which the cell alternates runs over straight lines and re-orientations. This erratic motion may be influenced by external factors, like chemicals, nutrients, the extra-cellular matrix, in the sense that the cell measures the external field and elaborates the signal eventually adapting its dynamics. We propose a kinetic transport equation implementing a velocity-jump process in which the transition probability takes into account a double bias, which acts, respectively, on the choice of the direction of motion and of the speed. The double bias "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1906.11039","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:41:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"nvOgulZoWjL3131fd8gdyp3Bw5rzSXaMwaoopjqy8bnObmS4gBWG7JKzQWCt3Hfc4SooF6kqjwfZx0S31s4+Bg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-21T22:46:21.163937Z"},"content_sha256":"a315e6049e5a4c5ac48986c342960f28ab5fe9ce21eee47a0b8a987927fa27b5","schema_version":"1.0","event_id":"sha256:a315e6049e5a4c5ac48986c342960f28ab5fe9ce21eee47a0b8a987927fa27b5"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/ZZCE7GGKUVMXWTCWR7JMFLWACR/bundle.json","state_url":"https://pith.science/pith/ZZCE7GGKUVMXWTCWR7JMFLWACR/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/ZZCE7GGKUVMXWTCWR7JMFLWACR/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-21T22:46:21Z","links":{"resolver":"https://pith.science/pith/ZZCE7GGKUVMXWTCWR7JMFLWACR","bundle":"https://pith.science/pith/ZZCE7GGKUVMXWTCWR7JMFLWACR/bundle.json","state":"https://pith.science/pith/ZZCE7GGKUVMXWTCWR7JMFLWACR/state.json","well_known_bundle":"https://pith.science/.well-known/pith/ZZCE7GGKUVMXWTCWR7JMFLWACR/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:ZZCE7GGKUVMXWTCWR7JMFLWACR","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"2aa3ca5ba81a7fdf67327bd2060021d587c45f154fb6943cdf0de2ffa9cee250","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-06-17T16:15:30Z","title_canon_sha256":"1d323304028c880ef5dcffbb81ec1f6a151fdc7a21bdc22488ea871bc76a2fe2"},"schema_version":"1.0","source":{"id":"1906.11039","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1906.11039","created_at":"2026-05-17T23:41:52Z"},{"alias_kind":"arxiv_version","alias_value":"1906.11039v3","created_at":"2026-05-17T23:41:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1906.11039","created_at":"2026-05-17T23:41:52Z"},{"alias_kind":"pith_short_12","alias_value":"ZZCE7GGKUVMX","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_16","alias_value":"ZZCE7GGKUVMXWTCW","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_8","alias_value":"ZZCE7GGK","created_at":"2026-05-18T12:33:33Z"}],"graph_snapshots":[{"event_id":"sha256:a315e6049e5a4c5ac48986c342960f28ab5fe9ce21eee47a0b8a987927fa27b5","target":"graph","created_at":"2026-05-17T23:41:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Cells move by run and tumble, a kind of dynamics in which the cell alternates runs over straight lines and re-orientations. This erratic motion may be influenced by external factors, like chemicals, nutrients, the extra-cellular matrix, in the sense that the cell measures the external field and elaborates the signal eventually adapting its dynamics. We propose a kinetic transport equation implementing a velocity-jump process in which the transition probability takes into account a double bias, which acts, respectively, on the choice of the direction of motion and of the speed. The double bias ","authors_text":"Luigi Preziosi, Nadia Loy","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-06-17T16:15:30Z","title":"Kinetic models with non-local sensing determining cell polarization and speed according to independent cues"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1906.11039","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:da0a63606b667cb470bc864a3067c9ac205b4dd5d2d063bb97035a368aee7ec3","target":"record","created_at":"2026-05-17T23:41:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"2aa3ca5ba81a7fdf67327bd2060021d587c45f154fb6943cdf0de2ffa9cee250","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-06-17T16:15:30Z","title_canon_sha256":"1d323304028c880ef5dcffbb81ec1f6a151fdc7a21bdc22488ea871bc76a2fe2"},"schema_version":"1.0","source":{"id":"1906.11039","kind":"arxiv","version":3}},"canonical_sha256":"ce444f98caa5597b4c568fd2c2aec01479bde6462abf927320198014ed05dc08","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ce444f98caa5597b4c568fd2c2aec01479bde6462abf927320198014ed05dc08","first_computed_at":"2026-05-17T23:41:52.713893Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:41:52.713893Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"t/GFZoSlIxK4xv5yfVlLCPUBykY9t9/5g4HS0aOph7lz60cuomASpq46sFZFk8IYr+qcprk7VMCZuFa6kBV1BQ==","signature_status":"signed_v1","signed_at":"2026-05-17T23:41:52.714411Z","signed_message":"canonical_sha256_bytes"},"source_id":"1906.11039","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:da0a63606b667cb470bc864a3067c9ac205b4dd5d2d063bb97035a368aee7ec3","sha256:a315e6049e5a4c5ac48986c342960f28ab5fe9ce21eee47a0b8a987927fa27b5"],"state_sha256":"33c712629026bc52ceb70830e5ceae528d58b7af28b4d0907900c33ec65e829f"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"gxw04vyc6OzWCsWKU9U1Y1MqLxAg/rdaD0bat1G5wQDfgRKpgIIa7IrzAHmAY7r35ZKU93BAfQdVmtGjU39ABQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-21T22:46:21.165908Z","bundle_sha256":"44f7c1f8e29bc2c20c799773991774bd8df6ae9e21d1b51582916a78b777092d"}}