The authors introduce dynamic token adaptation to combine DNA language models with single-cell foundation models, and show that mutating GATA4's promoter in silico shifts predicted target gene embeddings in fetal cardiomyocytes.
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Multi-modal single-cell foundation models via dynamic token adaptation
The authors introduce dynamic token adaptation to combine DNA language models with single-cell foundation models, and show that mutating GATA4's promoter in silico shifts predicted target gene embeddings in fetal cardiomyocytes.