Across 15 pathway-informed deep learning models, randomized pathway annotations matched or beat the biologically informed versions, suggesting that observed gains come from sparsity rather than biological content.
Ball, Judith A
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
q-bio.QM 1years
2025 1verdicts
CONDITIONAL 1representative citing papers
citing papers explorer
-
Sparsity is All You Need: Rethinking Biological Pathway-Informed Approaches in Deep Learning
Across 15 pathway-informed deep learning models, randomized pathway annotations matched or beat the biologically informed versions, suggesting that observed gains come from sparsity rather than biological content.