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Classical-to-Quantum Sequence Encoding in Genomics

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arxiv 2304.10786 v1 pith:AE5B5OIN submitted 2023-04-21 quant-ph cs.LG

classification quant-phcs.LG
keywords encodingalgorithmsbioinformaticsclassical-to-quantumdatafieldsdiversegenomics
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DNA sequencing allows for the determination of the genetic code of an organism, and therefore is an indispensable tool that has applications in Medicine, Life Sciences, Evolutionary Biology, Food Sciences and Technology, and Agriculture. In this paper, we present several novel methods of performing classical-to-quantum data encoding inspired by various mathematical fields, and we demonstrate these ideas within Bioinformatics. In particular, we introduce algorithms that draw inspiration from diverse fields such as Electrical and Electronic Engineering, Information Theory, Differential Geometry, and Neural Network architectures. We provide a complete overview of the existing data encoding schemes and show how to use them in Genomics. The algorithms provided utilise lossless compression, wavelet-based encoding, and information entropy. Moreover, we propose a contemporary method for testing encoded DNA sequences using Quantum Boltzmann Machines. To evaluate the effectiveness of our algorithms, we discuss a potential dataset that serves as a sandbox environment for testing against real-world scenarios. Our research contributes to developing classical-to-quantum data encoding methods in the science of Bioinformatics by introducing innovative algorithms that utilise diverse fields and advanced techniques. Our findings offer insights into the potential of Quantum Computing in Bioinformatics and have implications for future research in this area.

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Cited by 1 Pith paper

Reviewed papers in the Pith corpus that reference this work. Sorted by Pith novelty score. Full citation record

  1. QI-MPC: A Hybrid Quantum-Inspired Model Predictive Control for Learning Optimal Policies

    quant-ph 2025-04 reject novelty 4.0 of 10

    A hybrid quantum-classical control algorithm using variational quantum circuits is tested on five systems, with theoretical claims about when it outperforms classical MPC, but the evidence is not convincing.

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