Pith Number

pith:FZAEOBS2

pith:2025:FZAEOBS2Y7XIMWIDTKSMGVCMIK

not attested not anchored not stored refs pending

Large Language Model is Secretly a Protein Sequence Optimizer

Jianan Canal Li, Jiaxing He, Li-Ping Liu, Soha Hassoun, Xiaohui Chen, Xiaolin Xu, Yinkai Wang, Yuanqi Du

arxiv:2501.09274 v2 · 2025-01-16 · cs.LG · cs.AI · q-bio.QM

Open paper page JSON Open Graph Bundle Merged state Verified badge What is a Pith Number?

Add to your LaTeX paper

\usepackage{pith}
\pithnumber{FZAEOBS2Y7XIMWIDTKSMGVCMIK}

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Record completeness

1 Bitcoin timestamp

2 Internet Archive

3 Author claim open · sign in to claim

4 Citations open

5 Replications open

✓ Portable graph bundle live · download bundle · merged state

The bundle contains the canonical record plus signed events. A mirror can host it anywhere and recompute the same current state with the deterministic merge algorithm.

Cited by

2 papers in Pith

Towards Diverse Scientific Hypothesis Search with Large Language Models

Towards an AI co-scientist

Receipt and verification

First computed	2026-07-05T10:02:10.184364Z
Builder	pith-number-builder-2026-05-17-v1
Signature	Pith Ed25519 (`pith-v1-2026-05`) · public key
Schema	pith-number/v1.0

Canonical hash

2e4047065ac7ee8659039aa4c3544c42a7987a6538612d7af986d0e544421d24

Aliases

arxiv: 2501.09274 · arxiv_version: 2501.09274v2 · doi: 10.48550/arxiv.2501.09274 · pith_short_12: FZAEOBS2Y7XI · pith_short_16: FZAEOBS2Y7XIMWID · pith_short_8: FZAEOBS2

Agent API

Resolver JSON Graph JSON Events JSON Schema Signing key

Verify this Pith Number yourself

curl -sH 'Accept: application/ld+json' https://pith.science/pith/FZAEOBS2Y7XIMWIDTKSMGVCMIK \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: 2e4047065ac7ee8659039aa4c3544c42a7987a6538612d7af986d0e544421d24

Canonical record JSON

{
  "metadata": {
    "abstract_canon_sha256": "e226ac4c661b257588a1203507ec203d0bb9484a455631af00ba84554fedbfab",
    "cross_cats_sorted": [
      "cs.AI",
      "q-bio.QM"
    ],
    "license": "http://creativecommons.org/licenses/by/4.0/",
    "primary_cat": "cs.LG",
    "submitted_at": "2025-01-16T03:44:16Z",
    "title_canon_sha256": "6570c877050baf4b3d0182b6bca5db0d460ea138c9410b2c4e9cb06069ba3b86"
  },
  "schema_version": "1.0",
  "source": {
    "id": "2501.09274",
    "kind": "arxiv",
    "version": 2
  }
}