pith:PXWFVVF6
Effective interaction between helical bio-molecules
Simulations of helical DNA show that effective forces between strands switch between attraction and repulsion depending on their relative twist and can strengthen or weaken nonmonotonically with added salt.
arxiv:physics/9912053 v1 · 1999-12-29 · physics.bio-ph · physics.chem-ph · physics.comp-ph · q-bio
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\pithnumber{PXWFVVF6UNMLXPQF7P4DKHTSKK}
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Claims
the sign of the force depends sensitively on the relative orientation. For intermolecular distances smaller than 6Å it can be both attractive and repulsive. Furthermore we report a nonmonotonic behaviour of the effective force for increasing salt concentration.
The primitive model of electrolytes with an explicit double-helix charge pattern sufficiently captures the nonlinear screening physics of real B-DNA at the studied distances and salt concentrations.
Simulations of explicit double-helix B-DNA charge patterns reveal orientation-dependent effective forces that switch sign below 6 Å and exhibit nonmonotonic salt dependence beyond linear Debye-Hückel screening.
Receipt and verification
| First computed | 2026-07-04T16:15:38.893987Z |
|---|---|
| Builder | pith-number-builder-2026-05-17-v1 |
| Signature | Pith Ed25519
(pith-v1-2026-05) · public key |
| Schema | pith-number/v1.0 |
Canonical hash
7dec5ad4bea358bbbe05fbf8351e7252a2973aa59c91c838fc1105354ec6bbcb
Aliases
· · · · ·Agent API
Verify this Pith Number yourself
curl -sH 'Accept: application/ld+json' https://pith.science/pith/PXWFVVF6UNMLXPQF7P4DKHTSKK \
| jq -c '.canonical_record' \
| python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: 7dec5ad4bea358bbbe05fbf8351e7252a2973aa59c91c838fc1105354ec6bbcb
Canonical record JSON
{
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"cross_cats_sorted": [
"physics.chem-ph",
"physics.comp-ph",
"q-bio"
],
"license": "",
"primary_cat": "physics.bio-ph",
"submitted_at": "1999-12-29T17:05:26Z",
"title_canon_sha256": "5b7eeea8906ee62cd913a5b8c5df0007aaa1d92b2f26f580d9daa1c7e673f448"
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"source": {
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"kind": "arxiv",
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