The paper shows that quasi-linkage equilibrium persists at low migration rates between two populations and provides analytical inference relations for estimating additive fitness and epistatic interactions from whole-genome time-series data.
Selection.The model for natural selection is based on a fitness function F that can be understood as proportional to the expected number of offspring of an individual of genotype g
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Fitness Inference in Presence of Migrations between Coupled Evolving Populations
The paper shows that quasi-linkage equilibrium persists at low migration rates between two populations and provides analytical inference relations for estimating additive fitness and epistatic interactions from whole-genome time-series data.