Dose prioritization and inter-dose intervals in multi-dose vaccines can shift the epidemic threshold, with absolute priority to first doses at low vaccination rates and optimized scheduling at high rates under homogeneous mixing.
Voysey et al., The Lancet 397, 881 (2021)
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When to Boost: How Dose Timing Determines the Epidemic Threshold
Dose prioritization and inter-dose intervals in multi-dose vaccines can shift the epidemic threshold, with absolute priority to first doses at low vaccination rates and optimized scheduling at high rates under homogeneous mixing.