An algebraic approach defines semi-algebraic parameter sets from underlying polynomial structures in evolutionary processes before likelihood maximization, showing compatibility with existing statistical EvAM models while adding parameter-space information.
Accumulation of genetic and epigenetic alterations in normal cells and cancer risk.npj Precision Oncology, 3(1):1–8
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An Algebraic Approach to Evolutionary Accumulation Models
An algebraic approach defines semi-algebraic parameter sets from underlying polynomial structures in evolutionary processes before likelihood maximization, showing compatibility with existing statistical EvAM models while adding parameter-space information.