An optimal control problem is formulated and analyzed for chemotherapy and antiangiogenic therapies in a Keller-Segel glioblastoma model with oxytaxis, proving existence of optimal solutions and deriving first-order optimality conditions.
(2022) Optimal control of a Fisher-KPP type model arising in chemotherapy for brain tumors.Pure and Applied Functional Analysis,7(5) 1637-1655
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Optimal control of therapies related to an oxytaxis glioblastoma model
An optimal control problem is formulated and analyzed for chemotherapy and antiangiogenic therapies in a Keller-Segel glioblastoma model with oxytaxis, proving existence of optimal solutions and deriving first-order optimality conditions.