An optimal control problem is formulated and analyzed for chemotherapy and antiangiogenic therapies in a Keller-Segel glioblastoma model with oxytaxis, proving existence of optimal solutions and deriving first-order optimality conditions.
(1969).Quelques m´ ethodes de r´ esolution des probl` emes aux limites non lin´ eaires
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Optimal control of therapies related to an oxytaxis glioblastoma model
An optimal control problem is formulated and analyzed for chemotherapy and antiangiogenic therapies in a Keller-Segel glioblastoma model with oxytaxis, proving existence of optimal solutions and deriving first-order optimality conditions.