This perspective piece reviews limitations of top-down and bottom-up methods for detecting group differences in genetic value and concludes that such claims require considerable caution.
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
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Tread lightly interpreting group differences in genetic risk
This perspective piece reviews limitations of top-down and bottom-up methods for detecting group differences in genetic value and concludes that such claims require considerable caution.