Bucket Masking improves protein fitness prediction by up to 14% over random masking by preferentially masking structurally coupled residue groups on four downstream tasks.
Learning protein fitness landscapes with deep mutational scanning data from multiple sources.Cell Systems, 14(8):706–721.e5, August 2023
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Structure-Aware Masking for Protein Representation Learning
Bucket Masking improves protein fitness prediction by up to 14% over random masking by preferentially masking structurally coupled residue groups on four downstream tasks.