A diffuse interface mixture formulation coupled to immersed boundary method enables simulation of oxygen transport and metabolism with deforming RBCs in straight and networked capillaries, indicating autonomous RBC regulation that produces homogeneous tissue oxygenation.
Krogh, The progress of physiology, Science 70 (1929) 200–2 04
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Diffuse interface approach to oxygen transport and metabolism under blood flow dynamics in microcirculations
A diffuse interface mixture formulation coupled to immersed boundary method enables simulation of oxygen transport and metabolism with deforming RBCs in straight and networked capillaries, indicating autonomous RBC regulation that produces homogeneous tissue oxygenation.