FLAME applies fine-grained list-wise alignment and Group Relative Policy Optimization to large language models for generating safe medication recommendations by sequentially adding or removing drugs.
Safedrug: Dual molecular graph encoders for recommending effective and safe drug combinations
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Fine-grained List-wise Alignment for Generative Medication Recommendation
FLAME applies fine-grained list-wise alignment and Group Relative Policy Optimization to large language models for generating safe medication recommendations by sequentially adding or removing drugs.