PATH gene embeddings in a graph transformer achieve 0.8766 F1 on pancancer metastasis prediction (8.8% over SOTA) and identify disease-state pathway rewiring.
SOAT1 elevated in PCa tissues, correlated with metastasis and Gleason score; knockdown suppresses SCD1-driven lipogenesis and inhibits tumor growth in vivo
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Graph Transformer-Based Pathway Embedding for Cancer Prognosis
PATH gene embeddings in a graph transformer achieve 0.8766 F1 on pancancer metastasis prediction (8.8% over SOTA) and identify disease-state pathway rewiring.