A multi-stage framework with prompt calibration, rule-based filtering, semantic checks, judge LLM review, and predictive validation enables trustworthy LLM extraction of substance use disorder diagnoses from nearly 920,000 clinical notes, achieving F1 of 0.80 and superior care-engagement prediction.
Survey and analysis of hallucinations in large language models: Attribution to prompting strategies or model behavior
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A Multi-Stage Validation Framework for Trustworthy Large-scale Clinical Information Extraction using Large Language Models
A multi-stage framework with prompt calibration, rule-based filtering, semantic checks, judge LLM review, and predictive validation enables trustworthy LLM extraction of substance use disorder diagnoses from nearly 920,000 clinical notes, achieving F1 of 0.80 and superior care-engagement prediction.