AMPGAN v3 generates non-canonical AMPs with D-amino acids and modifications using two discriminators for stability, validated with two active candidates in vitro, alongside the PepCraft multi-agent discovery framework.
Antimicrobial Peptides: Opportunities and Challenges in Overcoming Resistance , volume=
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Agentic Discovery of Non-Canonical Antimicrobial Peptides with AMPGAN v3
AMPGAN v3 generates non-canonical AMPs with D-amino acids and modifications using two discriminators for stability, validated with two active candidates in vitro, alongside the PepCraft multi-agent discovery framework.