A hybrid agent-based and continuum model for oncolytic virotherapy with immune response shows agreement between discrete and PDE descriptions in 2D but reveals that overly rapid immune activation can reduce therapeutic efficacy due to stochastic effects.
Wodarz , Viruses as antitumor weapons: Defining conditions for tumor remission, Cancer Research, 61 (2001), pp
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
q-bio.PE 1years
2024 1verdicts
CONDITIONAL 1representative citing papers
citing papers explorer
-
A hybrid discrete-continuum modelling approach for the interactions of the immune system with oncolytic viral infections
A hybrid agent-based and continuum model for oncolytic virotherapy with immune response shows agreement between discrete and PDE descriptions in 2D but reveals that overly rapid immune activation can reduce therapeutic efficacy due to stochastic effects.