Proposes a bias-corrected estimator for the second arm in a two-arm platform trial with non-concurrent controls and interim analysis on the first arm, using time-adjusted regression.
Current state-of-the-art and gaps in platform trials: 10 things you should know, insights from EU-PEARL.Eclinicalmedicine, 67
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On the inclusion of non-concurrent controls in platform trials with an interim analysis
Proposes a bias-corrected estimator for the second arm in a two-arm platform trial with non-concurrent controls and interim analysis on the first arm, using time-adjusted regression.